PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23512537-6 2013 CYP3A4 and CYP3A5 metabolized BDP via hydroxylation ([M4] and [M6]) and dehydrogenation ([M5]) at similar rates; CYP3A7 did not metabolize BDP. Beclomethasone 30-33 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 0-6 23512537-11 2013 These studies show that CYP3A4 and CYP3A5 metabolize BDP to inactive metabolites and suggest that differences in the expression or function of these enzymes in the lung and/or liver could influence BDP disposition in humans. Beclomethasone 53-56 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 24-30 12538830-4 2003 About 4-fold induction was detected by nanomolar concentrations of dexamethasone and also by budenoside and beclomethasone dipropionate, glucocorticoids used for the inhalation treatment of bronchial asthma, whereas the CYP3A4 inducers mifepristone (RU486), rifampicin, clotrimazole, and nifedipine were without effect. Beclomethasone 108-135 cytochrome P450 family 3 subfamily A member 4 Homo sapiens 220-226