PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34815794-3 2021 Methods: We addressed the clinical dilemma of NAC by developing ultrasmall gold nanoclusters (1-2 nm) capped with NAC (denoted as Au NCs-NAC) as a nanozyme-based antioxidant defense system for AKI alleviation. Gold 130-132 synuclein alpha Homo sapiens 46-49 18464436-3 2008 In this paper, alpha-synuclein fibrils were used as a template for palladium (Pd), gold (Au) and copper (Cu) nanoparticle chains synthesis. Gold 89-91 synuclein alpha Homo sapiens 15-30 34677358-5 2021 Moreover, the utilization of rabbit-type monoclonal antibody (alpha-syn-RmAb) immobilized on Au films allows the SPR platform to have a high affinity-selectivity binding performance compared to mouse-type monoclonal antibodies as a common bioreceptor for capturing alpha-syn molecules. Gold 93-95 synuclein alpha Homo sapiens 265-274 34815794-3 2021 Methods: We addressed the clinical dilemma of NAC by developing ultrasmall gold nanoclusters (1-2 nm) capped with NAC (denoted as Au NCs-NAC) as a nanozyme-based antioxidant defense system for AKI alleviation. Gold 130-132 synuclein alpha Homo sapiens 114-117 34815794-3 2021 Methods: We addressed the clinical dilemma of NAC by developing ultrasmall gold nanoclusters (1-2 nm) capped with NAC (denoted as Au NCs-NAC) as a nanozyme-based antioxidant defense system for AKI alleviation. Gold 130-132 synuclein alpha Homo sapiens 137-140 28626495-3 2015 In this study, the binding of the protein alpha-synuclein to citrate and (16-mercaptohexadecyl) trimethylammonium bromide (MTAB) coated 12 nm Au NPs is examined by heteronuclear single quantum coherence NMR spectroscopy to provide site-specific measurements of protein-nanoparticle binding. Gold 142-144 synuclein alpha Homo sapiens 42-57 27474283-4 2016 The strong interaction of NAC and AuNPs through Au-S bond could lead to the aggregation of AuNPs, but the formation of NAC-Hg-NAC complex decreased the affinity between NAC and AuNPs and resulted in an anti-aggregation effect. Gold 34-36 synuclein alpha Homo sapiens 119-122 27474283-4 2016 The strong interaction of NAC and AuNPs through Au-S bond could lead to the aggregation of AuNPs, but the formation of NAC-Hg-NAC complex decreased the affinity between NAC and AuNPs and resulted in an anti-aggregation effect. Gold 34-36 synuclein alpha Homo sapiens 119-122 27474283-4 2016 The strong interaction of NAC and AuNPs through Au-S bond could lead to the aggregation of AuNPs, but the formation of NAC-Hg-NAC complex decreased the affinity between NAC and AuNPs and resulted in an anti-aggregation effect. Gold 34-36 synuclein alpha Homo sapiens 119-122 21038326-0 2010 A photoelectrochemical immunosensor based on Au-doped TiO2 nanotube arrays for the detection of alpha-synuclein. Gold 45-47 synuclein alpha Homo sapiens 96-111 25622115-0 2015 Au nanostructured surfaces for electrochemical and localized surface plasmon resonance-based monitoring of alpha-synuclein-small molecule interactions. Gold 0-2 synuclein alpha Homo sapiens 107-122 23477540-4 2013 alpha-Syn was determined to interact with 20 and 90 nm Au NPs via multilayered adsorption: a strong electrostatic interaction between alpha-syn and Au NPs in the hard corona and a weaker noncovalent protein-protein interaction in the soft corona. Gold 55-57 synuclein alpha Homo sapiens 0-9 23477540-4 2013 alpha-Syn was determined to interact with 20 and 90 nm Au NPs via multilayered adsorption: a strong electrostatic interaction between alpha-syn and Au NPs in the hard corona and a weaker noncovalent protein-protein interaction in the soft corona. Gold 148-150 synuclein alpha Homo sapiens 0-9 23477540-5 2013 Spectroscopic and light-scattering titrations led to the determinations of binding constants for the Au NP alpha-syn coronas: for the hard corona on 20 nm Au NPs, the equilibrium association constant was 2.9 +- 1.1 x 10(9) M(-1) (for 360 +- 70 alpha-syn/NP), and on 90 nm Au NPs, the hard corona association constant was 9.5 +- 0.8 x 10(10) M(-1) (for 5300 +- 700 alpha-syn/NP). Gold 101-103 synuclein alpha Homo sapiens 107-116 23477540-5 2013 Spectroscopic and light-scattering titrations led to the determinations of binding constants for the Au NP alpha-syn coronas: for the hard corona on 20 nm Au NPs, the equilibrium association constant was 2.9 +- 1.1 x 10(9) M(-1) (for 360 +- 70 alpha-syn/NP), and on 90 nm Au NPs, the hard corona association constant was 9.5 +- 0.8 x 10(10) M(-1) (for 5300 +- 700 alpha-syn/NP). Gold 101-103 synuclein alpha Homo sapiens 244-253 23477540-5 2013 Spectroscopic and light-scattering titrations led to the determinations of binding constants for the Au NP alpha-syn coronas: for the hard corona on 20 nm Au NPs, the equilibrium association constant was 2.9 +- 1.1 x 10(9) M(-1) (for 360 +- 70 alpha-syn/NP), and on 90 nm Au NPs, the hard corona association constant was 9.5 +- 0.8 x 10(10) M(-1) (for 5300 +- 700 alpha-syn/NP). Gold 101-103 synuclein alpha Homo sapiens 244-253 23477540-5 2013 Spectroscopic and light-scattering titrations led to the determinations of binding constants for the Au NP alpha-syn coronas: for the hard corona on 20 nm Au NPs, the equilibrium association constant was 2.9 +- 1.1 x 10(9) M(-1) (for 360 +- 70 alpha-syn/NP), and on 90 nm Au NPs, the hard corona association constant was 9.5 +- 0.8 x 10(10) M(-1) (for 5300 +- 700 alpha-syn/NP). Gold 155-157 synuclein alpha Homo sapiens 107-116 23477540-5 2013 Spectroscopic and light-scattering titrations led to the determinations of binding constants for the Au NP alpha-syn coronas: for the hard corona on 20 nm Au NPs, the equilibrium association constant was 2.9 +- 1.1 x 10(9) M(-1) (for 360 +- 70 alpha-syn/NP), and on 90 nm Au NPs, the hard corona association constant was 9.5 +- 0.8 x 10(10) M(-1) (for 5300 +- 700 alpha-syn/NP). Gold 155-157 synuclein alpha Homo sapiens 107-116 21038326-2 2010 In this paper, we utilized Au-doped TiO(2) nanotube arrays to design a photoelectrochemical immunosensor for the detection of alpha-SYN. Gold 27-29 synuclein alpha Homo sapiens 126-135 21038326-5 2010 Moreover, the Au-doped TiO(2) nanotubes formed effective antibody immobilization arrays and immobilized primary antibodies (Ab(1)) with high stability and bioactivity to bind target alpha-SYN. Gold 14-16 synuclein alpha Homo sapiens 182-191