PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27816763-0	2017	PPARalpha protects against trans-fatty-acid-containing diet-induced steatohepatitis.	Trans Fatty Acids	27-43	peroxisome proliferator activated receptor alpha	Mus musculus	0-9	
27816763-5	2017	Ppara-null mice fed a TFA-containing diet showed more severe hepatic steatosis and liver damage compared with similarly treated wild-type mice, as revealed by increased hepatic triglyceride (TG) contents and serum alanine aminotransferase activities.	Trans Fatty Acids	22-25	peroxisome proliferator activated receptor alpha	Mus musculus	0-5	
27816763-6	2017	While the TFA-rich diet increased the hepatic expression of enzymes involved in de novo FA synthesis and decreased TG-hydrolyzing enzymes in both genotypes, the expression of FA-catabolizing enzymes was decreased in Ppara-null mice, resulting in more severe hepatosteatosis.	Trans Fatty Acids	10-13	peroxisome proliferator activated receptor alpha	Mus musculus	216-221	
27816763-7	2017	Additionally, the expression levels of key contributors to inflammation, such as osteopontin, were increased, and nuclear factor-kappa B was activated in TFA-containing diet-fed Ppara-null mice.	Trans Fatty Acids	154-157	peroxisome proliferator activated receptor alpha	Mus musculus	178-183	
27816763-9	2017	Collectively, these results suggest a protective role for PPARalpha in the pathological changes in the liver following TFA consumption.	Trans Fatty Acids	119-122	peroxisome proliferator activated receptor alpha	Mus musculus	58-67	
27816763-10	2017	PPARalpha might prevent TFA-containing diet-induced steatohepatitis.	Trans Fatty Acids	24-27	peroxisome proliferator activated receptor alpha	Mus musculus	0-9