PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24964617-6	2014	RESULTS: The section of the IL-6, TNF-alpha, IL-1beta and IL-8 were the highest when THP-1 cells were exposed to NiSO4, DNCB and K2Cr2O7 for 6h, PPDA and TDI for 12h.	Dinitrochlorobenzene	120-124	GLI family zinc finger 2	Homo sapiens	85-90	
29587260-10	2018	In a human monocyte THP-1 model, verbascoside could suppress DNCB-induced upregulation of CD86 and CD54 at the cell surface, the secretion of the proinflammatory cytokines TNF-alpha and IL-6, and the activation of NFkappaB signaling in a dose-dependent manner.	Dinitrochlorobenzene	61-65	GLI family zinc finger 2	Homo sapiens	20-25	
16311011-3	2006	As regards pre-culturing time, the expression of CD86 on DNCB-treated THP-1 cells tended to be higher after 48h and 72h pre-culture compared with other time points evaluated.	Dinitrochlorobenzene	57-61	GLI family zinc finger 2	Homo sapiens	70-75	
19336971-0	2009	Modification of cell-surface thiols elicits activation of human monocytic cell line THP-1: possible involvement in effect of haptens 2,4-dinitrochlorobenzene and nickel sulfate.	Dinitrochlorobenzene	133-157	GLI family zinc finger 2	Homo sapiens	84-89	
19033392-9	2009	A significant inhibition of the expression of hmox1 and nqo1 mRNAs and CD86 expression was found in 1-chloro 2,4-dinitrobenzene-treated THP-1 cells preincubated with N-acetyl cysteine, a glutathione precursor.	Dinitrochlorobenzene	100-127	GLI family zinc finger 2	Homo sapiens	136-141	
18303184-0	2008	Role of MAPK signaling pathway in the activation of dendritic type cell line, THP-1, induced by DNCB and NiSO4.	Dinitrochlorobenzene	96-100	GLI family zinc finger 2	Homo sapiens	78-83	
18303184-4	2008	In this study, we investigated the signaling pathways in THP-1 cells activated by two representative allergens, DNCB and NiSO(4).	Dinitrochlorobenzene	112-116	GLI family zinc finger 2	Homo sapiens	57-62	
17624238-5	2007	Up-regulation of CD86 following in vitro incubation of DCs and THP-1 cells with DNCB, PPD, TMS and Na2PtCl4, but not with SDS, was observed.	Dinitrochlorobenzene	80-84	GLI family zinc finger 2	Homo sapiens	63-68	
17624238-8	2007	On THP-1 cells, only DNCB up-regulated CD80 expression.	Dinitrochlorobenzene	21-25	GLI family zinc finger 2	Homo sapiens	3-8	
16314067-1	2006	In order to seek a novel biomarker for predicting skin sensitization, changes in the gene expression profile of THP-1 cells on exposure to 2,4-dinitrochlorobenzene (DNCB), p-phenylenediamine (pPD) and nickel sulfate (Ni) were assessed using oligo-DNA microarrays.	Dinitrochlorobenzene	139-163	GLI family zinc finger 2	Homo sapiens	112-117	
16314067-1	2006	In order to seek a novel biomarker for predicting skin sensitization, changes in the gene expression profile of THP-1 cells on exposure to 2,4-dinitrochlorobenzene (DNCB), p-phenylenediamine (pPD) and nickel sulfate (Ni) were assessed using oligo-DNA microarrays.	Dinitrochlorobenzene	165-169	GLI family zinc finger 2	Homo sapiens	112-117	
16314067-4	2006	Secretion of MIP-1 beta from THP-1 was detected after 24-h treatment with sensitizers such as DNCB, Ni, 2-mercaptobenzothiazole (2-MBT) and cobalt sulfate (Co), while pPD and non-sensitizers such as sodium dodecyl sulfate (SDS) and benzalkonium chloride (BC) had no effect.	Dinitrochlorobenzene	94-98	GLI family zinc finger 2	Homo sapiens	29-34	
16311011-4	2006	Next, we investigated the effect of chemical treatment time, and found that induction of CD86 expression on THP-1 cells by DNCB reached a plateau after 24h.	Dinitrochlorobenzene	123-127	GLI family zinc finger 2	Homo sapiens	108-113	
12650676-8	2003	Interestingly, the naive THP-1 cells responded only to DNCB and the response to the sensitizer was more distinct than cytokine-treated THP-1 cells.	Dinitrochlorobenzene	55-59	GLI family zinc finger 2	Homo sapiens	25-30	
12650676-10	2003	Furthermore, with treatment of DNCB, naive THP-1 cells showed augmented expression of HLA, CD80 and secretion of IL-1 beta.	Dinitrochlorobenzene	31-35	GLI family zinc finger 2	Homo sapiens	43-48	
12423654-7	2002	A synergistic effect was observed when DNCB and IFN-alpha were added simultaneously to a culture of THP-1 cells.	Dinitrochlorobenzene	39-43	GLI family zinc finger 2	Homo sapiens	100-105	
32413475-6	2020	imDCs function in vitro and the surface antigens changes both in imDCs and THP-1 after 24 h of 2,4-dinitrochlorobenzene (DNCB) exposure were determined.	Dinitrochlorobenzene	95-119	GLI family zinc finger 2	Homo sapiens	75-80