PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30293230-3 2019 We evaluated whether the olive-derived polyphenol hydroxytyrosol combined with omega-3 fatty acids and curcumin would reduce CRP and musculoskeletal symptoms in breast cancer patients receiving adjuvant hormonal therapies. Fatty Acids, Omega-3 79-98 C-reactive protein Homo sapiens 125-128 30097364-13 2019 CONCLUSIONS: The use of a nutritional supplement enriched with O3FA is associated with a greater preoperative weight loss, reduced postoperative pain and decreased postoperative levels of C reactive protein. Fatty Acids, Omega-3 63-67 C-reactive protein Homo sapiens 188-206 30293230-10 2019 CONCLUSIONS: The combination of hydroxytyrosol, omega-3 fatty acids, and curcumin reduced inflammation as indicated by a reduction in CRP and reduced pain in patients with aromatase-induced musculoskeletal symptoms. Fatty Acids, Omega-3 48-67 C-reactive protein Homo sapiens 134-137 30212928-0 2018 Effect of omega 3 fatty acids on C-reactive protein and interleukin-6 in patients with advanced nonsmall cell lung cancer. Fatty Acids, Omega-3 10-29 C-reactive protein Homo sapiens 33-51 30125457-6 2019 Significant beneficial effects from marine n-3 FA supplementation were, however, seen in secondary endpoints plasma triglycerides, plasma high-sensitivity C-reactive protein, and brachial artery flow-mediated dilation. Fatty Acids, Omega-3 43-49 C-reactive protein Homo sapiens 155-173 29271576-11 2018 This suggested that there is insufficient evidence to conclude the benefit of omega-3 fatty acids oral supplementation in reducing serum levels of CRP, IL-6 and TNF-alpha in patients with CKD. Fatty Acids, Omega-3 78-97 C-reactive protein Homo sapiens 147-150 29570616-8 2018 Meta-analyses indicated significant reduction in CRP levels by omega-3 fatty acids (Random model effect: -0.667 mg/L, p < 0.001) and vitamin E (fixed model effect: -0.257 mg/L, p = 0.005). Fatty Acids, Omega-3 63-82 C-reactive protein Homo sapiens 49-52 29938621-2 2018 Curcumin and omega-3 fatty acids can exert neuroprotective effects through modulation of IL-6 gene expression and CRP levels. Fatty Acids, Omega-3 13-32 C-reactive protein Homo sapiens 114-117 29173690-1 2017 BACKGROUND: Studies have shown that omega-3 fatty acids reduce the concentrations of eicosanoids, cytokines, chemokines, C-reactive protein (CRP) and other inflammatory mediators. Fatty Acids, Omega-3 36-55 C-reactive protein Homo sapiens 121-139 29173690-1 2017 BACKGROUND: Studies have shown that omega-3 fatty acids reduce the concentrations of eicosanoids, cytokines, chemokines, C-reactive protein (CRP) and other inflammatory mediators. Fatty Acids, Omega-3 36-55 C-reactive protein Homo sapiens 141-144 24973862-7 2015 Furthermore, a significant reduction in serum high sensitivity C-reactive protein (hs-CRP) levels was seen after omega-3 fatty acid supplementation compared with placebo (-236.3 +- 1541.9 vs. 898.6 +- 2292.7 ng/mL, P = 0.03). Fatty Acids, Omega-3 113-131 C-reactive protein Homo sapiens 63-81 26908433-6 2016 Saturated fat intake was associated with increased CRP, sTNFRII, TNFalpha, and IL1beta, whereas eicosapentaenoic acid + docosahexaenoic acid (EPA+DHA) intake (diet or total) was associated with decreased CRP, TNFalpha, and IL1beta. Fatty Acids, Omega-3 0-13 C-reactive protein Homo sapiens 51-54 25445629-1 2014 Various studies have demonstrated the impact of omega-3 fatty acids on the concentration of C reactive protein (CRP), pro-inflammatory eicosanoids, cytokines, chemokines and other inflammatory mediators. Fatty Acids, Omega-3 48-67 C-reactive protein Homo sapiens 92-110 25445629-1 2014 Various studies have demonstrated the impact of omega-3 fatty acids on the concentration of C reactive protein (CRP), pro-inflammatory eicosanoids, cytokines, chemokines and other inflammatory mediators. Fatty Acids, Omega-3 48-67 C-reactive protein Homo sapiens 112-115 23338919-0 2013 Comment on: efficacy of omega-3 fatty acid supplementation on serum levels of tumour necrosis factor-alpha, C-reactive protein and interleukin-2 in type 2 diabetes mellitus patients. Fatty Acids, Omega-3 24-42 C-reactive protein Homo sapiens 108-126 24505395-0 2014 Effect of marine-derived n-3 polyunsaturated fatty acids on C-reactive protein, interleukin 6 and tumor necrosis factor alpha: a meta-analysis. Fatty Acids, Omega-3 25-56 C-reactive protein Homo sapiens 60-78 24505395-4 2014 Marine-derived n-3 PUFAs supplementation showed a lowering effect on Marine-derived n-3 PUFAs supplementation had a significant lowering effect on TNF-alpha, IL-6 and CRP in three groups of subjects (subjects with chronic non-autoimmune disease, subjects with chronic autoimmune disease and healthy subjects). Fatty Acids, Omega-3 15-24 C-reactive protein Homo sapiens 167-170 24505395-4 2014 Marine-derived n-3 PUFAs supplementation showed a lowering effect on Marine-derived n-3 PUFAs supplementation had a significant lowering effect on TNF-alpha, IL-6 and CRP in three groups of subjects (subjects with chronic non-autoimmune disease, subjects with chronic autoimmune disease and healthy subjects). Fatty Acids, Omega-3 84-93 C-reactive protein Homo sapiens 167-170 24505395-9 2014 CONCLUSIONS: Marine-derived n-3 PUFAs supplementation had a significant lowering effect on CRP, IL-6 and TNF-alpha level. Fatty Acids, Omega-3 28-37 C-reactive protein Homo sapiens 91-94 23302662-10 2013 Conversely, a DP reflecting a high n-6:n-3 fatty acid intake ratio was positively and significantly associated with elevated CRP (adjusted OR 1 15; 95% CI 1 00, 1 32). Fatty Acids, Omega-3 39-53 C-reactive protein Homo sapiens 125-128 23361365-2 2013 Several epidemiological studies have reported that dietary intake of n-3 polyunsaturated fatty acids (n-3 PUFAs) is inversely associated with serum CRP concentration. Fatty Acids, Omega-3 69-100 C-reactive protein Homo sapiens 148-151 23361365-2 2013 Several epidemiological studies have reported that dietary intake of n-3 polyunsaturated fatty acids (n-3 PUFAs) is inversely associated with serum CRP concentration. Fatty Acids, Omega-3 102-111 C-reactive protein Homo sapiens 148-151 23361365-4 2013 The aims of this study were to examine the effect of the n-3 PUFAs, docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA), on the modulation of IL-6-induced CRP expression and to explore its possible mechanisms. Fatty Acids, Omega-3 57-66 C-reactive protein Homo sapiens 163-166 31667003-0 2013 Relationship of Omega-3 Fatty Acids on C-Reactive Protein and Homocysteine in Haitian and African Americans with and without Type 2 Diabetes. Fatty Acids, Omega-3 16-35 C-reactive protein Homo sapiens 39-57 22113248-0 2012 Association of serum n-3 polyunsaturated fatty acids with C-reactive protein in men. Fatty Acids, Omega-3 21-52 C-reactive protein Homo sapiens 58-76 23023905-0 2012 Efficacy of omega-3 fatty acid supplementation on serum levels of tumour necrosis factor-alpha, C-reactive protein and interleukin-2 in type 2 diabetes mellitus patients. Fatty Acids, Omega-3 12-30 C-reactive protein Homo sapiens 96-114 23023905-2 2012 This study aimed to determine the effects of omega-3 fatty acid supplementation on the serum levels of C-reactive protein (CRP), interleukin (IL)-2 and tumour necrosis factor-alpha (TNF-alpha) in type 2 diabetes mellitus patients. Fatty Acids, Omega-3 45-63 C-reactive protein Homo sapiens 103-121 23023905-2 2012 This study aimed to determine the effects of omega-3 fatty acid supplementation on the serum levels of C-reactive protein (CRP), interleukin (IL)-2 and tumour necrosis factor-alpha (TNF-alpha) in type 2 diabetes mellitus patients. Fatty Acids, Omega-3 45-63 C-reactive protein Homo sapiens 123-126 22569435-0 2012 Effect of treatment with omega-3 fatty acids on C-reactive protein and tumor necrosis factor-alfa in hemodialysis patients. Fatty Acids, Omega-3 25-44 C-reactive protein Homo sapiens 48-66 22569435-3 2012 The aim of this study is to review the alterations in serum levels of TNF-alpha, CRP and other parameters caused by omega-3 supplementation in dialysis patients. Fatty Acids, Omega-3 116-123 C-reactive protein Homo sapiens 81-84 22536073-13 2012 CONCLUSION: "Directly observed treatment" with an omega-3 based supplement (as opposed to a pure protein supplement) showed beneficial effects on the lipid profile, and C-reactive protein levels. Fatty Acids, Omega-3 50-57 C-reactive protein Homo sapiens 169-187 21543294-6 2011 Effect of n-3 polyunsaturated fatty acids on inflammation was evaluated with high sensitivity C-reactive protein level measurements. Fatty Acids, Omega-3 10-41 C-reactive protein Homo sapiens 94-112 19625064-2 2009 Fasting concentrations of interleukin-6 (IL-6) and C-reactive protein (CRP), key inflammatory mediators, decrease after sustained n-3 polyunsaturated fatty acid (PUFA) intake; however, the ability of n-3 PUFA to attenuate postprandial inflammatory responses is not well studied. Fatty Acids, Omega-3 130-160 C-reactive protein Homo sapiens 71-74 18343384-0 2008 Dietary intake of n-3 polyunsaturated fatty acids is inversely associated with CRP levels, especially among male smokers. Fatty Acids, Omega-3 18-49 C-reactive protein Homo sapiens 79-82 19352379-0 2009 An inverse relationship between plasma n-3 fatty acids and C-reactive protein in healthy individuals. Fatty Acids, Omega-3 39-54 C-reactive protein Homo sapiens 59-77 19185299-5 2009 RESULTS: After multivariable adjustment, n-3 fatty acid levels (DHA+EPA) were inversely associated with CRP and IL-6. Fatty Acids, Omega-3 41-55 C-reactive protein Homo sapiens 104-107 19185299-6 2009 The inverse association of n-3 fatty acids with CRP and IL-6 was not modified by demographics, body-mass index, smoking, LDL-cholesterol, or statin use (p values for interaction>0.1). Fatty Acids, Omega-3 27-42 C-reactive protein Homo sapiens 48-51 18343384-1 2008 OBJECTIVE: To examine whether dietary intake of n-3 polyunsaturated fatty acid (n-3PUFA) is associated with serum C-reactive protein (CRP) levels with regard to smoking status in the Japanese general population in a cross-sectional study. Fatty Acids, Omega-3 48-78 C-reactive protein Homo sapiens 114-132 18343384-1 2008 OBJECTIVE: To examine whether dietary intake of n-3 polyunsaturated fatty acid (n-3PUFA) is associated with serum C-reactive protein (CRP) levels with regard to smoking status in the Japanese general population in a cross-sectional study. Fatty Acids, Omega-3 48-78 C-reactive protein Homo sapiens 134-137 17546842-13 2007 No change during the control period regarding baseline occurred when placebo was randomized to be given first; however, when it followed omega-3 supplementation, CRP and SAA recovered, whereas WBC and fibronection remained depressed during those 2 weeks (7500 +/- 2100/mm3 and 393.2 +/- 75.8 mg/dL, P<0.05). Fatty Acids, Omega-3 137-144 C-reactive protein Homo sapiens 162-165 18343384-1 2008 OBJECTIVE: To examine whether dietary intake of n-3 polyunsaturated fatty acid (n-3PUFA) is associated with serum C-reactive protein (CRP) levels with regard to smoking status in the Japanese general population in a cross-sectional study. Fatty Acids, Omega-3 80-87 C-reactive protein Homo sapiens 114-132 18343384-1 2008 OBJECTIVE: To examine whether dietary intake of n-3 polyunsaturated fatty acid (n-3PUFA) is associated with serum C-reactive protein (CRP) levels with regard to smoking status in the Japanese general population in a cross-sectional study. Fatty Acids, Omega-3 80-87 C-reactive protein Homo sapiens 134-137 19083425-0 2008 Total n-3 polyunsaturated fatty acid intake is inversely associated with serum C-reactive protein in young Japanese women. Fatty Acids, Omega-3 6-36 C-reactive protein Homo sapiens 79-97 19083425-7 2008 After adjustment for possible confounding factors including body mass index, a significant inverse association was seen between total n-3 polyunsaturated fatty acid intake and elevated CRP. Fatty Acids, Omega-3 134-164 C-reactive protein Homo sapiens 185-188 19083425-12 2008 In conclusion, total n-3 polyunsaturated fatty acid intake showed an independent inverse association with elevated serum CRP concentration in a group of young Japanese women. Fatty Acids, Omega-3 21-51 C-reactive protein Homo sapiens 121-124 17586424-0 2007 The effect of n-3 fatty acids on C-reactive protein levels in patients with chronic renal failure. Fatty Acids, Omega-3 14-29 C-reactive protein Homo sapiens 33-51 17545695-7 2007 A multiple regression analysis showed that, especially in the middle tertile of long-chain n-3 PUFAs (eicosapentaenoic acid and docosahexaenoic acid) intake, CRP was inversely related to the intake of oleic acid and linoleic acid in both sexes and to the intake of alpha-linolenic acid in women. Fatty Acids, Omega-3 91-100 C-reactive protein Homo sapiens 158-161 16825699-1 2006 BACKGROUND: Several studies have reported that the intake of n-3 polyunsaturated fatty acids (PUFAs) or fish is inversely associated with serum C-reactive protein (CRP) concentrations, but few studies have evaluated the relations between serum CRP concentrations and consumption of n-3 PUFAs derived from marine products in populations with a diet rich in marine products. Fatty Acids, Omega-3 61-92 C-reactive protein Homo sapiens 144-162 16825699-1 2006 BACKGROUND: Several studies have reported that the intake of n-3 polyunsaturated fatty acids (PUFAs) or fish is inversely associated with serum C-reactive protein (CRP) concentrations, but few studies have evaluated the relations between serum CRP concentrations and consumption of n-3 PUFAs derived from marine products in populations with a diet rich in marine products. Fatty Acids, Omega-3 61-92 C-reactive protein Homo sapiens 164-167 16825699-8 2006 CONCLUSIONS: Greater intake of n-3 PUFAs derived from marine products, as measured with a self-administered questionnaire, was independently related to a lower prevalence of high CRP concentrations in this older Japanese population with a diet rich in marine products. Fatty Acids, Omega-3 31-40 C-reactive protein Homo sapiens 179-182 16825699-9 2006 Our findings suggest that even very high intakes of n-3 PUFAs may lower serum CRP concentrations. Fatty Acids, Omega-3 52-61 C-reactive protein Homo sapiens 78-81 16234304-12 2006 CONCLUSIONS: In this community-based sample, PUFAs, and especially total n-3 fatty acids, were independently associated with lower levels of proinflammatory markers (IL-6, IL-1ra, TNFalpha, C-reactive protein) and higher levels of antiinflammatory markers (soluble IL-6r, IL-10, TGFbeta) independent of confounders. Fatty Acids, Omega-3 73-88 C-reactive protein Homo sapiens 190-208 15458276-7 2004 Supplementation with n-3 FA and a low n-6 FA intake decreased serum sTNF-R p55 and CRP levels in patients with RA. Fatty Acids, Omega-3 21-27 C-reactive protein Homo sapiens 83-86 16054558-0 2005 The effects of consumption of omega3 fatty acid-enriched eggs on insulin and CRP. Fatty Acids, Omega-3 30-47 C-reactive protein Homo sapiens 77-80 15226473-4 2004 C-reactive protein (CRP) levels were 29% lower among those in the highest quintile of total (n-3) fatty acids, compared with the lowest quintile; interleukin-6 (IL-6) levels were 23% lower, E-selectin levels 10% lower, soluble intracellular adhesion molecule (sICAM-1) levels 7% lower, and soluble vascular adhesion molecule (sVCAM-1) levels 8% lower. Fatty Acids, Omega-3 92-109 C-reactive protein Homo sapiens 0-18 15226473-4 2004 C-reactive protein (CRP) levels were 29% lower among those in the highest quintile of total (n-3) fatty acids, compared with the lowest quintile; interleukin-6 (IL-6) levels were 23% lower, E-selectin levels 10% lower, soluble intracellular adhesion molecule (sICAM-1) levels 7% lower, and soluble vascular adhesion molecule (sVCAM-1) levels 8% lower. Fatty Acids, Omega-3 92-109 C-reactive protein Homo sapiens 20-23 15226473-7 2004 Total (n-3) fatty acids had an inverse relation with CRP (beta = -0.44, P = 0.007), IL-6 (beta = -0.26, P = 0.009), E-selectin (beta = -0.17, P = 0.004), sICAM-1 (beta = -0.07, P = 0.02), and sVCAM-1 (beta = -0.10, P = 0.004). Fatty Acids, Omega-3 6-23 C-reactive protein Homo sapiens 53-56 12821543-3 2003 After adjustment for other predictors of inflammation, intake of the n-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) was inversely associated with plasma levels of sTNF-R1 and sTNF-R2 (P=0.03 and P<0.001, respectively) and somewhat less so for C-reactive protein (P=0.08). Fatty Acids, Omega-3 69-84 C-reactive protein Homo sapiens 274-292 12716789-6 2003 Saturated-to-omega-3 and saturated-to-omega-6 FA ratios were significantly and positively associated with C-reactive protein (P < 0.0001) and IL-6 (P < 0.001), respectively. Fatty Acids, Omega-3 13-20 C-reactive protein Homo sapiens 106-124 12654170-0 2003 The effect of dietary n-3 fatty acids on serum concentrations of C-reactive protein: a dose-response study. Fatty Acids, Omega-3 22-37 C-reactive protein Homo sapiens 65-83 34455435-3 2021 Long-Term Outcomes Study to Assess Statin Residual Risk with Epanova in High Cardiovascular Risk Patients with Hypertriglyceridaemia (STRENGTH), can be explained by differences in the effect of active and comparator oils on lipid traits and C-reactive protein. Fatty Acids, Omega-3 61-68 C-reactive protein Homo sapiens 241-259 10696629-7 2000 Treatment with omega-3 fatty acids resulted in greater disease activity as detected by a significant increase in platelet count, erythrocyte sedimentation rate, C-reactive protein, and total fecal nitrogen excretion. Fatty Acids, Omega-3 15-34 C-reactive protein Homo sapiens 161-179 34405148-5 2021 Results: Based on post-hoc analyses, hs-CRP levels were significantly lower in the collagen (p=0.026) and collagen+omega-3 (p=0.044) groups compared to the control group, at week three. Fatty Acids, Omega-3 115-122 C-reactive protein Homo sapiens 40-43 34516692-9 2021 Reducing effects of omega-3 supplementation compared to control group were also observed in the levels of ESR and CRP after treatment (p<0.001 for CRP and p=0.02 for ESR). Fatty Acids, Omega-3 20-27 C-reactive protein Homo sapiens 114-117 34516692-9 2021 Reducing effects of omega-3 supplementation compared to control group were also observed in the levels of ESR and CRP after treatment (p<0.001 for CRP and p=0.02 for ESR). Fatty Acids, Omega-3 20-27 C-reactive protein Homo sapiens 147-150 34183020-4 2021 The use of omega-3 fatty acid supplements was reported in 856 out of 1002 recreational athletes, and the association between supplement use and the exercise-induced CRP response was assessed. Fatty Acids, Omega-3 11-29 C-reactive protein Homo sapiens 165-168 34183020-7 2021 Regular users of omega-3 fatty acid supplements had significantly lower basal and exercise-induced CRP levels as compared to non-users (n = 348, p < 0.001). Fatty Acids, Omega-3 17-35 C-reactive protein Homo sapiens 99-102 34183020-11 2021 CONCLUSION: Basal CRP levels were reduced, and the exercise-induced CRP response was attenuated in healthy recreational cyclists who used omega-3 fatty acid supplements regularly. Fatty Acids, Omega-3 138-156 C-reactive protein Homo sapiens 18-21 34183020-11 2021 CONCLUSION: Basal CRP levels were reduced, and the exercise-induced CRP response was attenuated in healthy recreational cyclists who used omega-3 fatty acid supplements regularly. Fatty Acids, Omega-3 138-156 C-reactive protein Homo sapiens 68-71 33991364-2 2021 A recent randomized clinical trial demonstrated that daily supplementation with high-dose marine omega-3 FAs lowered plasma triglyceride and C-reactive protein levels (1). Fatty Acids, Omega-3 97-108 C-reactive protein Homo sapiens 141-159 33081175-10 2020 Supplementing n-3 fatty acids, probiotics, synbiotics, and trace elements increased antioxidant enzymes and reduced hs-CRP and MDA. Fatty Acids, Omega-3 14-29 C-reactive protein Homo sapiens 119-122 32799935-11 2021 The data suggest that supplementation of omega-3 fatty acids could reduce the inflammatory state in women with PCOS, through a decrease in hs-CRP and an increase in adiponectin levels. Fatty Acids, Omega-3 41-60 C-reactive protein Homo sapiens 142-145 33450081-13 2021 Omega-3 FAs also suppressed C-reactive protein levels and neutrophil-to-lymphocyte ratio in Gr. Fatty Acids, Omega-3 0-11 C-reactive protein Homo sapiens 28-46 32921364-2 2020 We tested the hypothesis that parenteral omega-3 FA from a lipid emulsion that includes fish oil could be beneficial in patients with predicted SAP by reducing C-reactive protein (CRP) concentration (primary outcome), and modulating the inflammatory response and improving clinical outcome (secondary outcomes). Fatty Acids, Omega-3 41-51 C-reactive protein Homo sapiens 160-178 32921364-2 2020 We tested the hypothesis that parenteral omega-3 FA from a lipid emulsion that includes fish oil could be beneficial in patients with predicted SAP by reducing C-reactive protein (CRP) concentration (primary outcome), and modulating the inflammatory response and improving clinical outcome (secondary outcomes). Fatty Acids, Omega-3 41-51 C-reactive protein Homo sapiens 180-183 33520859-8 2020 However, omega-3 PUFA significantly increased serum concentrations of HDL-cholesterol (WMD: 3.10; 95% CI: 0.18, 6.03) and reduced C-reactive protein (WMD: -1.85; 95% CI: -2.61, -1.09). Fatty Acids, Omega-3 9-21 C-reactive protein Homo sapiens 130-148 31827125-1 2019 The purpose of this systematic review and meta-analysis was to investigate omega-3 fatty acids" influence on 12 inflammatory biomarkers-LDL, HDL, total cholesterol, TG, HbA1c, Apo AI, Apo AII, Apo B, CRP, TNF-alpha, glucose, and fasting blood glucose among diabetic and cardiovascular disease (CVD) patients. Fatty Acids, Omega-3 75-94 C-reactive protein Homo sapiens 200-203 30231792-7 2020 However, notably decreased high sensitivity C-reactive protein (hs-CRP) is revealed after omega-3 fatty acids supplementation (std. Fatty Acids, Omega-3 90-109 C-reactive protein Homo sapiens 44-62 31902378-7 2020 Omega-3 fatty acids administration was also associated with a significant reduction in high sensitivity C-reactive protein (P=0.006) and malondialdehyde (P<0.001), and an increase in total nitrite (P<0.001) and total glutathione levels (P=0.006) when compared with the placebo. Fatty Acids, Omega-3 0-19 C-reactive protein Homo sapiens 104-122 31106659-4 2020 After 8 weeks of intervention, patients who received combined vitamin D3 and omega-3 fatty acids supplements compared with omega-3, vitamin D3, and placebo groups had significantly decreased CRP and TNF-alpha. Fatty Acids, Omega-3 77-96 C-reactive protein Homo sapiens 191-194 31106659-4 2020 After 8 weeks of intervention, patients who received combined vitamin D3 and omega-3 fatty acids supplements compared with omega-3, vitamin D3, and placebo groups had significantly decreased CRP and TNF-alpha. Fatty Acids, Omega-3 77-84 C-reactive protein Homo sapiens 191-194