PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 6409396-1 1983 There are two major R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur) activation pathways to 5-fluorouracil, one that is mediated by microsomal cytochrome P-450 oxidation at C-5" of the tetrahydrofuran moiety and one that is mediated by soluble enzymes. r,s-1-(tetrahydro-2-furanyl)-5-fluorouracil 20-63 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 149-165