PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17675415-3 2007 The crucial role of IL-1beta in inflammation has been highlighted by studies performed in caspase-1 knockout mice (casp1(-/-)), transgenic mice that lack mature IL-1beta and survive lethal doses of lypopolysaccharide (LPS). lypopolysaccharide 198-216 interleukin 1 beta Mus musculus 20-28