PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17186014-7 2007 Increased transgene expression following infection with an adenovirus expressing tumor necrosis factor-related apoptosis inducing ligand (TRAIL) was observed only in LNCaP cells treated with depsipeptide or MS-275. Depsipeptides 191-203 TNF superfamily member 10 Homo sapiens 81-136 17186014-7 2007 Increased transgene expression following infection with an adenovirus expressing tumor necrosis factor-related apoptosis inducing ligand (TRAIL) was observed only in LNCaP cells treated with depsipeptide or MS-275. Depsipeptides 191-203 TNF superfamily member 10 Homo sapiens 138-143 16849582-0 2006 Bortezomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity. Depsipeptides 15-27 TNF superfamily member 10 Homo sapiens 48-103 15771957-0 2005 Depsipeptide (FR901228) enhances the cytotoxic activity of TRAIL by redistributing TRAIL receptor to membrane lipid rafts. Depsipeptides 0-12 TNF superfamily member 10 Homo sapiens 59-64 15771957-0 2005 Depsipeptide (FR901228) enhances the cytotoxic activity of TRAIL by redistributing TRAIL receptor to membrane lipid rafts. Depsipeptides 0-12 TNF superfamily member 10 Homo sapiens 83-88 15771957-5 2005 Thus, studies were initiated to evaluate the ability of depsipeptide to enhance the cytotoxic activity of Ad5-TRAIL against human prostate tumor cells. Depsipeptides 56-68 TNF superfamily member 10 Homo sapiens 110-115 15771957-7 2005 Additionally, tumor cell killing by Ad5-TRAIL was higher following depsipeptide pretreatment. Depsipeptides 67-79 TNF superfamily member 10 Homo sapiens 40-45 15771957-9 2005 Investigation into the mechanism responsible for increased TRAIL responsiveness revealed increased levels of TRAIL-R1 and -R2 in membrane lipid rafts following depsipeptide treatment. Depsipeptides 160-172 TNF superfamily member 10 Homo sapiens 59-64 15771957-10 2005 These results indicate that depsipeptide is a potent agent for enhancing the activity of Ad5-TRAIL by multiple mechanisms, allowing for a more efficient use of Ad5-TRAIL as an antitumor therapy. Depsipeptides 28-40 TNF superfamily member 10 Homo sapiens 93-98 15771957-10 2005 These results indicate that depsipeptide is a potent agent for enhancing the activity of Ad5-TRAIL by multiple mechanisms, allowing for a more efficient use of Ad5-TRAIL as an antitumor therapy. Depsipeptides 28-40 TNF superfamily member 10 Homo sapiens 164-169 15608694-4 2004 We report that low concentrations of histone deacetylase (HDAC) inhibitors, such as depsipeptide, which alone failed to induce apoptosis, markedly sensitize CLL cells and other primary lymphoid malignancies to TRAIL-induced apoptosis. Depsipeptides 84-96 TNF superfamily member 10 Homo sapiens 210-215