PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11472266-3	2001	The mechanism of anticancer activity of the cryptophycins has been associated with their destabilization of microtubules and with their induction of bcl-2 phosphorylation leading to apoptosis.	Depsipeptides	44-57	BCL2 apoptosis regulator	Homo sapiens	149-154	
15059137-9	2004	BCL-2, BCL-XL and MCL-1 showed decreased expression in depsipeptide-treated samples.	Depsipeptides	55-67	BCL2 apoptosis regulator	Homo sapiens	0-5	
11269744-13	2001	Thus, cryptophycins are potent inducers of Bcl-2 phosphorylation.	Depsipeptides	6-19	BCL2 apoptosis regulator	Homo sapiens	43-48	
11269744-14	2001	The cryptophycins were more potent cytotoxic agents in Bcl-2-negative Calu-6 cells than in Bcl-2-positive H460 cells indicating that pathways triggered by Bcl-2 phosphorylation are involved in cryptophycin-induced lethality.	Depsipeptides	4-17	BCL2 apoptosis regulator	Homo sapiens	55-60	
11269744-14	2001	The cryptophycins were more potent cytotoxic agents in Bcl-2-negative Calu-6 cells than in Bcl-2-positive H460 cells indicating that pathways triggered by Bcl-2 phosphorylation are involved in cryptophycin-induced lethality.	Depsipeptides	4-17	BCL2 apoptosis regulator	Homo sapiens	91-96	
11269744-14	2001	The cryptophycins were more potent cytotoxic agents in Bcl-2-negative Calu-6 cells than in Bcl-2-positive H460 cells indicating that pathways triggered by Bcl-2 phosphorylation are involved in cryptophycin-induced lethality.	Depsipeptides	4-17	BCL2 apoptosis regulator	Homo sapiens	91-96