PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33164356-4	2020	The results showed that adenosine, epigoitrin, chlorogenic acid, caffeic acid, cichoric acid, corynoline, baicalin, wogonoside, wogonin and oroxylin A had a certain regulatory effect on inflammatory factor tumor necrosis factor(TNF-alpha), interleukin(IL-1beta) and IL-6 at specific concentrations in a dose-dependent manner.	baicalin	106-114	interleukin 6	Homo sapiens	266-270	
28829242-6	2017	We found that BA treatment led to remarkable reductions of OA-related proinflammatory gene expressions, including interleukin (IL)-6, tumor necrosis factor (TNF), chemokine (C-X-C motif) ligand 1 (CXCL1), and CXCL10.	baicalin	14-16	interleukin 6	Homo sapiens	114-132	
32537016-6	2020	In vitro, the results demonstrated that baicalin clearly inhibited the release of TNF-alpha, IL-6 and IL-1beta and promoted the expression of IL-10 in LPS-induced HT-29 cells, and significantly decreased LPS-induced HT-29 cell apoptosis by blockage of the PI3K/AKT signaling pathway.	baicalin	40-48	interleukin 6	Homo sapiens	93-97	
32537016-5	2020	In the present study, the results revealed that baicalin not only significantly alleviated TNBS-induced colitis by reducing the release of IL-6, TNF-alpha and IL-1beta and increasing the level of IL-10, but promoted the expression of tight-junction proteins ZO-1 and beta-catenin, which may have been achieved by blockage of the PI3K/AKT signaling pathway.	baicalin	48-56	interleukin 6	Homo sapiens	139-143	
29331857-7	2018	Baicalin alleviated IL-1beta-induced inflammatory injury, as it increased cell viability, decreased cell apoptosis and repressed the production of IL-6, IL-8 and TNF-alpha.	baicalin	0-8	interleukin 6	Homo sapiens	147-151	
28396833-11	2017	HMGB1, sRAGE, IL6 and TGFbeta1 levels in BALF were also reduced by baicalin treatment.	baicalin	67-75	interleukin 6	Homo sapiens	14-17	
28396833-13	2017	Furthermore, expression levels of HMGB1, RAGE, IL6 and TGFbeta1 in lung tissue were dramatically decreased by baicalin in a dosage-dependent manner.	baicalin	110-118	interleukin 6	Homo sapiens	47-50	
27043920-12	2016	In addition, baicalin also inhibited the productions of inflammatory cytokines such as IL-1beta, IL-6, IL-8 and TNF-alpha and suppressed the phosphorylation of JAK2, STAT5, IKKbeta, IkappaBalpha and the nuclear translocation of NF-kappaB (p65) subunit in LPS-stimulated human mast cells.	baicalin	13-21	interleukin 6	Homo sapiens	97-101	
27045865-14	2016	CONCLUSIONS: Berberine, baicalin and geniposide could neutralize LPS by binding with lipid A and then reduce the release of IL-6 and TNF-alpha induced by LPS.	baicalin	24-32	interleukin 6	Homo sapiens	124-128