PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16056106-7	2005	GCDC stimulated reactive oxygen species generation and release of cytochrome c and apoptosis-inducing factor, which were significantly inhibited by the antioxidants, cyclosporin A, and TUDC.	ursodoxicoltaurine	185-189	cytochrome c, somatic	Homo sapiens	66-78	
17559149-7	2007	However, inhibition studies performed using tauroursodeoxycholic acid (TUDCA) demonstrate its ability to inhibit caspase-4 and caspase-3/7 activation, mitochondrial cytochrome c release, and caspase-3 cleavage induced by ZAAT and to promote cell survival.	ursodoxicoltaurine	44-69	cytochrome c, somatic	Homo sapiens	165-177	
17559149-7	2007	However, inhibition studies performed using tauroursodeoxycholic acid (TUDCA) demonstrate its ability to inhibit caspase-4 and caspase-3/7 activation, mitochondrial cytochrome c release, and caspase-3 cleavage induced by ZAAT and to promote cell survival.	ursodoxicoltaurine	71-76	cytochrome c, somatic	Homo sapiens	165-177	
12773247-0	2003	[Effect of Tauroursodeoxycholic acid on cytochrome C-mediated apoptosis in HepG2 cells].	ursodoxicoltaurine	11-36	cytochrome c, somatic	Homo sapiens	40-52	
12773247-5	2003	Following incubation of HepG2 cells either with TDCA alone, or coincubation with TUDCA and TDCA, the releasing level of cytochrome c from mitochondria into cytosol was determined by western blot, also the activity of caspase-3, 8, 9.	ursodoxicoltaurine	81-86	cytochrome c, somatic	Homo sapiens	120-132	
12773247-8	2003	TUDCA significantly inhibited the release of cytochrome C from mitochondria into cytosol, and the activity of caspase-9, 3 (t > or = 13.00, P < 0.01), especially at 12 h, caspase-3 activity decreased by 54.9% (t = 16.88, P < 0.01) and 52.5%, however it had no obvious effect on the activity of caspase-8 (t = 1.94, P > 0.05).	ursodoxicoltaurine	0-5	cytochrome c, somatic	Homo sapiens	45-57	
12627974-0	2003	Tauroursodeoxycholic acid prevents Bax-induced membrane perturbation and cytochrome C release in isolated mitochondria.	ursodoxicoltaurine	0-25	cytochrome c, somatic	Homo sapiens	73-85	
12627974-3	2003	The mechanisms by which Bax induces and TUDCA inhibits release of cytochrome c are unclear.	ursodoxicoltaurine	40-45	cytochrome c, somatic	Homo sapiens	66-78