PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30416448-10 2018 In addition, resistin increased the mRNA expressions of proinflammatory cytokines tumor nuclear factor (TNF)alpha and interleukin (IL)-1beta, which were also prevented by TUDCA. ursodoxicoltaurine 171-176 interleukin 1 beta Homo sapiens 118-140 31877413-10 2020 Moreover, pretreatment with TUDCA restored suppression of TNF-alpha and IL-1beta expression and attenuated the enhanced viability of macrophages induced by gAcrp. ursodoxicoltaurine 28-33 interleukin 1 beta Homo sapiens 72-80 26355342-10 2015 In contrast, the LPS challenge is blocked by the ER stress inhibitor TUDCA, resulting in: CHOP downregulation, reduced caspase-1, caspase-11, caspase-3 activities, lowered interleukin-1beta secretion and rescue from cell death. ursodoxicoltaurine 69-74 interleukin 1 beta Homo sapiens 172-189 26902174-4 2016 Suppression of ER stress, using ER stress inhibitor tauroursodeoxycholic acid (TUDCA) or siRNA knockdown of IRE1alpha and GRP78, significantly downregulated LPS-, poly(I:C)- or IL-1beta-induced production of IL-6, IL-8, IL-1beta and MCP-1. ursodoxicoltaurine 52-77 interleukin 1 beta Homo sapiens 177-185 21280192-7 2011 TUDCA treatment decreased nuclear factor kappa B activation and the proinflammatory cytokines interleukin-6 and interleukin-1beta. ursodoxicoltaurine 0-5 interleukin 1 beta Homo sapiens 112-129