PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32790682-7	2020	On the other hand, mechanical stretching of isolated cardiac fibroblasts activated the IRE1alpha branch of the unfolded protein response pathway as well as induction of Col1A2 and TGFbeta gene expression ex vivo, which were all suppressed by tauroursodeoxycholic acid.	ursodoxicoltaurine	242-267	endoplasmic reticulum (ER) to nucleus signalling 1	Mus musculus	87-96	
30119197-9	2018	TUDCA dose-dependently suppressed the expression of inflammatory factors and IRE1alpha/TRAF2/NF-kappaB pathway activity in vitro, consistent with the in vivo results.	ursodoxicoltaurine	0-5	endoplasmic reticulum (ER) to nucleus signalling 1	Mus musculus	77-86	
30119197-10	2018	Therefore, TUDCA can effectively alleviate hepatic IR injury by down-regulating the activity of the IRE1alpha/TRAF2/NF-kappaB pathway to suppress the function of KCs.	ursodoxicoltaurine	11-16	endoplasmic reticulum (ER) to nucleus signalling 1	Mus musculus	100-109	
23667647-9	2013	TUDCA alleviated high-fat diet-induced decrease in SERCA2a and phosphorylation of phospholamban, increase in ER stress (GRP78/BiP, CHOP, phosphorylation of PERK, IRE1alpha and eIF2alpha), ultrastructural changes and mitochondrial permeation pore opening.	ursodoxicoltaurine	0-5	endoplasmic reticulum (ER) to nucleus signalling 1	Mus musculus	162-171