PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8771369-2	1996	We assessed the effect of imidazole inhibitors of cytochrome P-450 on the intracytoplasmic free Ca+2 ([Ca+2]i) response generated using the microsomal ATPase inhibitor thapsigargin (THG) to deplete the intracellular Ca+2 stores.	Thapsigargin	182-185	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	50-66	
15993852-3	2005	Thapsigargin-induced elevation of [Ca2+]i was inhibited by cytochrome P-450 inhibitors and by cytochrome P-450 epoxygenase inhibitor and was reverted by 11,12 EET addition.	Thapsigargin	0-12	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	59-75	
15993852-3	2005	Thapsigargin-induced elevation of [Ca2+]i was inhibited by cytochrome P-450 inhibitors and by cytochrome P-450 epoxygenase inhibitor and was reverted by 11,12 EET addition.	Thapsigargin	0-12	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	94-110	
15993852-7	2005	Thus, AA released by Ca2+-independent phospholipase A2 and AA metabolism through cytochrome P-450 pathway may be crucial molecular determinant in thapsigargin activation of SOC channels and store-operated Ca2+ entry pathway in 3T6 fibroblasts.	Thapsigargin	146-158	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	81-97	
15993852-8	2005	Moreover, EETs, the main cytochrome P-450 epoxygenase metabolites of AA, are involved in thapsigargin-stimulated Ca2+ influx.	Thapsigargin	89-101	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	25-41	
8771369-2	1996	We assessed the effect of imidazole inhibitors of cytochrome P-450 on the intracytoplasmic free Ca+2 ([Ca+2]i) response generated using the microsomal ATPase inhibitor thapsigargin (THG) to deplete the intracellular Ca+2 stores.	Thapsigargin	168-180	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	50-66	
8240252-8	1993	Inhibition of cytochrome P-450 with CO bubbled through platelet suspensions did not change calcium influx in resting cells and potentiated TG-induced calcium influx (160% of control calcium accumulation at 20 min).	Thapsigargin	139-141	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	14-30	
8068004-6	1994	Consistent with this idea, the imidazole cytochrome P-450 inhibitors miconazole, econazole, clotrimazole and ketoconazole inhibited the thapsigargin-elevated [Ca2+]i with pIC50 values of 7.1, 7.1, 7.1 and 5.8 respectively.	Thapsigargin	136-148	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	41-57