PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9849820-0	1998	Increased expression of tumor necrosis factor-alpha and decreased expression of thyroglobulin and thyroid peroxidase mRNA levels in the thyroids of iodide-treated BB/Wor rats.	Iodides	148-154	tumor necrosis factor	Rattus norvegicus	24-51	
8118227-6	1993	Inhibition of protein kinase A and protein kinase C by H7 or HA inhibited TSH-stimulated iodide transport, but did not block the TNF-alpha action, suggesting that the mechanism of TNF-alpha action on thyroid cells is independent of protein kinase A and C.	Iodides	89-95	tumor necrosis factor	Rattus norvegicus	180-189	
9316456-3	1997	In the present study, we found that TNF-alpha inhibits TSH-induced H2O2 production, which is an inevitable process for iodide organification, and hence thyroid hormone synthesis, in FRTL-5 thyroid cells.	Iodides	119-125	tumor necrosis factor	Rattus norvegicus	36-45	
9142647-4	1997	One prominent effect of TNF-alpha (and TGF-beta 1) on FRTL-5 cell function is suppression of iodide uptake, which is markedly stimulated by TSH.	Iodides	93-99	tumor necrosis factor	Rattus norvegicus	24-33	
9142647-6	1997	Na+/K(+)-ATPase activity, which drives iodide uptake by thyroid cells, is inhibited by TNF-alpha and TGF-beta.	Iodides	39-45	tumor necrosis factor	Rattus norvegicus	87-96