PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33352258-0	2021	In vitro screening for chemical inhibition of the iodide recycling enzyme, iodotyrosine deiodinase.	Iodides	50-56	iodotyrosine deiodinase	Homo sapiens	75-98	
33352258-1	2021	The iodide recycling enzyme, iodotyrosine deiodinase (IYD), is a largely unstudied molecular mechanism through which environmental chemicals can potentially cause thyroid disruption.	Iodides	4-10	iodotyrosine deiodinase	Homo sapiens	29-52	
33352258-1	2021	The iodide recycling enzyme, iodotyrosine deiodinase (IYD), is a largely unstudied molecular mechanism through which environmental chemicals can potentially cause thyroid disruption.	Iodides	4-10	iodotyrosine deiodinase	Homo sapiens	54-57	
26151430-1	2015	Reductive dehalogenation such as that catalyzed by iodotyrosine deiodinase (IYD) is highly unusual in aerobic organisms but necessary for iodide salvage from iodotyrosine generated during thyroxine biosynthesis.	Iodides	138-144	iodotyrosine deiodinase	Homo sapiens	51-74	
26151430-1	2015	Reductive dehalogenation such as that catalyzed by iodotyrosine deiodinase (IYD) is highly unusual in aerobic organisms but necessary for iodide salvage from iodotyrosine generated during thyroxine biosynthesis.	Iodides	138-144	iodotyrosine deiodinase	Homo sapiens	76-79	
25395621-2	2015	The flavoprotein iodotyrosine deiodinase (IYD) is responsible for iodide salvage by reductive deiodination of the iodotyrosine derivatives formed as byproducts of thyroid hormone biosynthesis.	Iodides	66-72	iodotyrosine deiodinase	Homo sapiens	17-40	
25395621-2	2015	The flavoprotein iodotyrosine deiodinase (IYD) is responsible for iodide salvage by reductive deiodination of the iodotyrosine derivatives formed as byproducts of thyroid hormone biosynthesis.	Iodides	66-72	iodotyrosine deiodinase	Homo sapiens	42-45	
17322488-1	2007	UNLABELLED: Iodotyrosine dehalogenase 1 (DEHAL1) is a transmembrane protein involved in the recycling of iodide in the human thyroid.	Iodides	105-111	iodotyrosine deiodinase	Homo sapiens	12-39	
25177024-4	2014	In addition, iodotyrosine deiodinase, which is involved in iodide salvage by catalyzing deiodination of iodinated by-products of thyroid hormone production, was recently identified as a possible new target for disruption of thyroid hormone homeostasis by environmental halogenated chemicals.	Iodides	59-65	iodotyrosine deiodinase	Homo sapiens	13-36	
19436071-0	2009	Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands.	Iodides	83-89	iodotyrosine deiodinase	Homo sapiens	21-44	
19436071-1	2009	The flavoprotein iodotyrosine deiodinase (IYD) salvages iodide from mono- and diiodotyrosine formed during the biosynthesis of the thyroid hormone thyroxine.	Iodides	56-62	iodotyrosine deiodinase	Homo sapiens	17-40	
19436071-1	2009	The flavoprotein iodotyrosine deiodinase (IYD) salvages iodide from mono- and diiodotyrosine formed during the biosynthesis of the thyroid hormone thyroxine.	Iodides	56-62	iodotyrosine deiodinase	Homo sapiens	42-45	
18434651-1	2008	DEHAL1 has been identified as the gene encoding iodotyrosine deiodinase in the thyroid, where it controls the reuse of iodide for thyroid hormone synthesis.	Iodides	119-125	iodotyrosine deiodinase	Homo sapiens	0-6	
24153409-2	2014	The role of both iodide and iodinated tyrosine derivatives is currently unknown in lower organisms, yet the presence of a key enzyme in iodide conservation, iodotyrosine deiodinase (IYD), is suggested by genomic data from a wide range of multicellular organisms as well as some bacteria.	Iodides	17-23	iodotyrosine deiodinase	Homo sapiens	182-185	
24153409-2	2014	The role of both iodide and iodinated tyrosine derivatives is currently unknown in lower organisms, yet the presence of a key enzyme in iodide conservation, iodotyrosine deiodinase (IYD), is suggested by genomic data from a wide range of multicellular organisms as well as some bacteria.	Iodides	136-142	iodotyrosine deiodinase	Homo sapiens	157-180	
24153409-2	2014	The role of both iodide and iodinated tyrosine derivatives is currently unknown in lower organisms, yet the presence of a key enzyme in iodide conservation, iodotyrosine deiodinase (IYD), is suggested by genomic data from a wide range of multicellular organisms as well as some bacteria.	Iodides	136-142	iodotyrosine deiodinase	Homo sapiens	182-185	
17322488-1	2007	UNLABELLED: Iodotyrosine dehalogenase 1 (DEHAL1) is a transmembrane protein involved in the recycling of iodide in the human thyroid.	Iodides	105-111	iodotyrosine deiodinase	Homo sapiens	41-47	
15289438-0	2004	Iodotyrosine dehalogenase 1 (DEHAL1) is a transmembrane protein involved in the recycling of iodide close to the thyroglobulin iodination site.	Iodides	93-99	iodotyrosine deiodinase	Homo sapiens	0-27	
16316988-1	2006	The enzyme responsible for iodide salvage in the thyroid, iodotyrosine deiodinase, was solubilized from porcine thyroid microsomes by limited proteolysis with trypsin.	Iodides	27-33	iodotyrosine deiodinase	Homo sapiens	58-81	
15289438-0	2004	Iodotyrosine dehalogenase 1 (DEHAL1) is a transmembrane protein involved in the recycling of iodide close to the thyroglobulin iodination site.	Iodides	93-99	iodotyrosine deiodinase	Homo sapiens	29-35