PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8274159-0	1993	Cytochrome P450 dependent N-hydroxylation of a guanidine (debrisoquine), microsomal catalysed reduction and further oxidation of the N-hydroxy-guanidine metabolite to the urea derivative.	Debrisoquin	58-70	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	11-15	
9865424-2	1998	Debrisoquine hydroxylase (CYP2D6), one member of the p450 hemoproteins, has polymorphic expression leading to poor metabolism of debrisoquine and similar compounds in approximately 7% of Caucasians.	Debrisoquin	129-141	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	53-57	
19698378-3	1995	In particular, activities of the P450-IID6 isoenzyme are related to the sparteine/debrisoquine oxidation polymorphism.	Debrisoquin	82-94	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	33-42	
1844820-1	1991	A variant CYP2D6(C) P450 protein was found in a liver characterized by deficient microsomal metabolism of bufuralol and sparteine, prototypical substrates for the debrisoquine-sparteine drug oxidation polymorphism.	Debrisoquin	163-175	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	20-24	
1844820-5	1991	The CYP2D6(C) P450, produced in HepG2 cells using vaccinia virus mediated cDNA expression displayed Km values toward bufuralol, debrisoquine and sparteine that were not significantly different from wild type CYP2D6.	Debrisoquin	128-140	cytochrome P450 family 2 subfamily B member 6	Homo sapiens	14-18