PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16636053-7 2006 Mutations of conserved hydrophobic residues (Ile-120, Ala-123, and Leu-124) located between the two Cys residues in the HCCH motif disrupt binding of the zinc-coordinating region to Cul5 and inhibit APOBEC3G degradation. Isoleucine 45-48 apolipoprotein B mRNA editing enzyme catalytic subunit 3G Homo sapiens 199-207