PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10574910-8	1999	These results suggest that the 341T --> C (Ile(114) --> Thr) common to the NAT2*5 cluster is sufficient for reduction in NAT2 protein expression, but that mechanisms for slow acetylator phenotype differ for NAT2 alleles that do not contain 341T --> C, such as the NAT2*6 and NAT2*14 clusters.	Isoleucine	46-49	N-acetyltransferase 2	Homo sapiens	81-85	
24333853-8	2014	However, substitution of Val231 by the bulkier isoleucine appears to alter enzyme substrate selectivity by decreasing the affinity towards NAT2 substrates and increasing the affinity towards NAT1 substrates.	Isoleucine	47-57	N-acetyltransferase 2	Homo sapiens	139-143	
20871037-8	2010	Ile(114) and Arg(197), which are mutation sites of NAT2*4 to NAT2*5 and NAT2*6, were located in the peripheral part of the positive field.	Isoleucine	0-3	N-acetyltransferase 2	Homo sapiens	51-55	
20871037-8	2010	Ile(114) and Arg(197), which are mutation sites of NAT2*4 to NAT2*5 and NAT2*6, were located in the peripheral part of the positive field.	Isoleucine	0-3	N-acetyltransferase 2	Homo sapiens	61-65	
20871037-8	2010	Ile(114) and Arg(197), which are mutation sites of NAT2*4 to NAT2*5 and NAT2*6, were located in the peripheral part of the positive field.	Isoleucine	0-3	N-acetyltransferase 2	Homo sapiens	61-65	
10574910-8	1999	These results suggest that the 341T --> C (Ile(114) --> Thr) common to the NAT2*5 cluster is sufficient for reduction in NAT2 protein expression, but that mechanisms for slow acetylator phenotype differ for NAT2 alleles that do not contain 341T --> C, such as the NAT2*6 and NAT2*14 clusters.	Isoleucine	46-49	N-acetyltransferase 2	Homo sapiens	127-131	
10574910-8	1999	These results suggest that the 341T --> C (Ile(114) --> Thr) common to the NAT2*5 cluster is sufficient for reduction in NAT2 protein expression, but that mechanisms for slow acetylator phenotype differ for NAT2 alleles that do not contain 341T --> C, such as the NAT2*6 and NAT2*14 clusters.	Isoleucine	46-49	N-acetyltransferase 2	Homo sapiens	127-131	
10574910-8	1999	These results suggest that the 341T --> C (Ile(114) --> Thr) common to the NAT2*5 cluster is sufficient for reduction in NAT2 protein expression, but that mechanisms for slow acetylator phenotype differ for NAT2 alleles that do not contain 341T --> C, such as the NAT2*6 and NAT2*14 clusters.	Isoleucine	46-49	N-acetyltransferase 2	Homo sapiens	127-131	
10574910-8	1999	These results suggest that the 341T --> C (Ile(114) --> Thr) common to the NAT2*5 cluster is sufficient for reduction in NAT2 protein expression, but that mechanisms for slow acetylator phenotype differ for NAT2 alleles that do not contain 341T --> C, such as the NAT2*6 and NAT2*14 clusters.	Isoleucine	46-49	N-acetyltransferase 2	Homo sapiens	127-131	
7915226-6	1994	One allele (NAT2(191)) contained a point mutation at nucleotide 191 [G-->A (Arg-->Gln)], whereas the other allele (NAT2(341/803)) contained two point mutations [341T-->C (Ile-->Thr); 803A-->G (Lys-->Arg)].	Isoleucine	180-183	N-acetyltransferase 2	Homo sapiens	12-16