PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19507198-3 2009 Based on homology studies and the crystal structure of the NADP(H)-dependent yeast alcohol dehydrogenase Adh6, three adjacent residues (Glu(221), Ile(222), and Ala(223)) were predicted to be involved in the coenzyme specificity of Bdh1 and were altered by site-directed mutagenesis. Isoleucine 146-149 NADP-dependent alcohol dehydrogenase Saccharomyces cerevisiae S288C 105-109