PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11516429-1	2001	beta(2)-adrenoceptors (beta(2)AR) are polymorphic at amino acid 164 (Thr or Ile) of the fourth transmembrane domain.	Isoleucine	76-79	adrenoceptor beta 2	Homo sapiens	0-21	
29053759-1	2017	The natural variant C491T (rs1800088) in ADRB2 gene substitutes Threonine to Isoleucine at 164th position in beta2AR and results in receptor sequestration and altered binding of agonists.	Isoleucine	77-87	adrenoceptor beta 2	Homo sapiens	41-46	
29053759-1	2017	The natural variant C491T (rs1800088) in ADRB2 gene substitutes Threonine to Isoleucine at 164th position in beta2AR and results in receptor sequestration and altered binding of agonists.	Isoleucine	77-87	adrenoceptor beta 2	Homo sapiens	109-116	
24328926-13	2014	Furthermore, Ile(116) acts as a gate for the movement of Tyr(244) towards TM-5 in the active state, a mechanism proposed previously for the beta2 -adrenoceptor.	Isoleucine	13-16	adrenoceptor beta 2	Homo sapiens	140-159	
17569809-4	2007	METHODS: Among 55 subjects, cardiac contractile response to the beta2-adrenergic receptor agonist terbutaline was assessed from the peak myocardial velocity of systolic shortening (Sm) in 18 subjects with the Ile-164 variant and 37 matched controls.	Isoleucine	209-212	adrenoceptor beta 2	Homo sapiens	64-89	
13680034-1	2003	OBJECTIVE: It has been shown that arginine to glycine (Arg16Gly), glutamine to glutamic acid (Gln27Glu) and threonine to isoleucine (Thr164Ile) exchanges in codons 16, 27 and 164, respectively, of the beta 2-adrenergic receptor (B2AR) gene significantly alter receptor function.	Isoleucine	121-131	adrenoceptor beta 2	Homo sapiens	201-227	
13680034-1	2003	OBJECTIVE: It has been shown that arginine to glycine (Arg16Gly), glutamine to glutamic acid (Gln27Glu) and threonine to isoleucine (Thr164Ile) exchanges in codons 16, 27 and 164, respectively, of the beta 2-adrenergic receptor (B2AR) gene significantly alter receptor function.	Isoleucine	121-131	adrenoceptor beta 2	Homo sapiens	229-233	
11516429-1	2001	beta(2)-adrenoceptors (beta(2)AR) are polymorphic at amino acid 164 (Thr or Ile) of the fourth transmembrane domain.	Isoleucine	76-79	adrenoceptor beta 2	Homo sapiens	23-32