PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10385247-7 1999 Mutations of threonine 100 and arginine 102 at the extracellular side of transmembrane II of the guinea-pig 5-HT1D receptor to the corresponding primate residues, isoleucine and histidine, respectively, enhanced its affinity for isochromans to that of the gorilla receptor, with little effects on its affinities for serotonin, sumatriptan and metergoline. Isoleucine 163-173 5-hydroxytryptamine receptor 1D Cavia porcellus 108-123