PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9616041-4 1998 Although each mutation caused reduced thermal stability, an amino acid substitution Thr-5-->Ile (T5I) exhibited marked thermal instability, suggesting that the amino-terminal of GPI is important for enzymatic stability. Isoleucine 95-98 glucose-6-phosphate isomerase Homo sapiens 181-184