PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17618155-0	2007	HSD17B10: a gene involved in cognitive function through metabolism of isoleucine and neuroactive steroids.	Isoleucine	70-80	hydroxysteroid 17-beta dehydrogenase 10	Homo sapiens	0-8	
28875337-0	2017	Clinical and molecular analysis of 6 Chinese patients with isoleucine metabolism defects: identification of 3 novel mutations in the HSD17B10 and ACAT1 gene.	Isoleucine	59-69	hydroxysteroid 17-beta dehydrogenase 10	Homo sapiens	133-141	
28875337-1	2017	Hydroxysteroid (17beta) dehydrogenase 10 (HSD10) and mitochondrial acetoacetyl-CoA thiolase (beta-KT) are two adjacent enzymes for the degradation of isoleucine, thus HSD10 and beta-KT deficiencies are confusing at an early stage because of nearly the same elevation of typical metabolites in urine, such as 2-methyl-3-hydroxybutyric acid (2M3HBA) and tiglylglycine (TG).	Isoleucine	150-160	hydroxysteroid 17-beta dehydrogenase 10	Homo sapiens	0-40	
19706438-0	2009	Mental retardation linked to mutations in the HSD17B10 gene interfering with neurosteroid and isoleucine metabolism.	Isoleucine	94-104	hydroxysteroid 17-beta dehydrogenase 10	Homo sapiens	46-54	
31654490-2	2019	The diagnosis is usually first suspected on finding elevated isoleucine degradation metabolites in urine, reflecting decreased MHBD activity.	Isoleucine	61-71	hydroxysteroid 17-beta dehydrogenase 10	Homo sapiens	127-131	
23834306-10	2013	The hypomethylation of the CpG island provides additional evidence for the variable escape of the HSD17B10 gene from X-chromosome inactivation which could influence the range of severity of HSD10 deficiency, an inherited error in isoleucine metabolism, in heterozygous females.	Isoleucine	230-240	hydroxysteroid 17-beta dehydrogenase 10	Homo sapiens	98-106	
15860413-3	2005	17Beta-HSD10/SCHAD is essential for the metabolism of isoleucine and branched-chain fatty acids.	Isoleucine	54-64	hydroxysteroid 17-beta dehydrogenase 10	Homo sapiens	13-18	
11102558-7	2000	Enzyme studies showed absent activity of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) in the mitochondrial oxidation of 2-methyl branched-chain fatty acids and isoleucine.	Isoleucine	166-176	hydroxysteroid 17-beta dehydrogenase 10	Homo sapiens	86-90