PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35245436-5	2022	Leucine and isoleucine, two branched-chain essential amino acids, strongly bind to and activate the E3 ubiquitin ligase Ubr1, targeting Plin2 for degradation.	Isoleucine	12-22	Ubr1 ubiquitin ligase	Drosophila melanogaster	120-124