PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11313422-6 2001 DMBA application induced pronounced production of PGE(2), IL-10, and TNF-alpha in the skin of XPA mice. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene 0-4 tumor necrosis factor Mus musculus 69-78 21670304-3 2011 Using an adoptive transfer strategy and the 7,12-dimethylbenz[alpha]anthracene/terephthalic acid (DMBA/TPA) two-stage model of skin carcinogenesis, we found that both B cells and TNF-alpha are critical for the development of DMBA/TPA-induced papilloma. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene 225-229 tumor necrosis factor Mus musculus 179-188 21670304-4 2011 Transfer of B cells from DMBA/TPA-treated wild-type mice to Tnf(-/-) mice rescued papilloma development to a wild-type level, a result not observed when B cells from Tnf(-/-) mice were transferred to Rag2(-/-) mice or when TNF-alpha was eliminated selectively in B cells. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene 25-29 tumor necrosis factor Mus musculus 223-232 21670304-6 2011 These data indicate that during DMBA/TPA-induced squamous carcinogenesis TNF-alpha mediates tumor-promoting activity via regulatory B cells that repress antitumor immunity. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene 32-36 tumor necrosis factor Mus musculus 73-82 11313422-9 2001 Excess production of PGE(2), TNF-alpha, and IL-10 after DMBA application may be involved in the enhanced local and systemic immunosuppression in DMBA-treated XPA mice. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene 145-149 tumor necrosis factor Mus musculus 29-38 10395330-3 1999 TNF-alpha(-/-) mice were resistant to development of benign and malignant skin tumors, whether induced by initiation with DMBA and promotion with TPA or by repeated dosing with DMBA. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene 122-126 tumor necrosis factor Mus musculus 0-9 10395330-3 1999 TNF-alpha(-/-) mice were resistant to development of benign and malignant skin tumors, whether induced by initiation with DMBA and promotion with TPA or by repeated dosing with DMBA. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene 177-181 tumor necrosis factor Mus musculus 0-9