PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17622315-8	2007	Treatment of DMBA-exposed animals with the liposomal formulation of DAS ensued in upregulation of p53wt and p21/Waf1, while levels of p53mut expression reduced down.	6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene	13-17	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	108-111	
1909512-7	1991	DMBA treatment induced binding of ras oncogene product ras p21 to [alpha 32P] GTP, altered estradiol metabolism by increasing the ratio of C16 alpha/C2 hydroxylation in favor of 16 alpha-OHE1 formation, and exhibited high frequency of MAL.	6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene	0-4	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	59-62	
33846306-10	2021	However, we found that epidermis lacking both p21 and ASK1 reacquires increased sensitivity to DMBA/TPA-induced tumorigenesis.	6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene	95-99	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	46-49	
27124579-8	2016	Furthermore, DMBA treatment triggered the upregulation of pro-apoptotic (Bid, Apaf1, Bax), cell death (Tnfrsf10b, Ripk1) and cell cycle inhibitor (Cdkn1a, Cdkn2c) genes in the mammary glands.	6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene	13-17	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	147-153	
20043298-7	2010	Initiation with DMBA led to a significant upregulation of p53 expression with a concomitant increase in p21(WAF1) levels in epidermal cells indicating induction of damage to the DNA.	6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene	16-20	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	104-107	
20043298-7	2010	Initiation with DMBA led to a significant upregulation of p53 expression with a concomitant increase in p21(WAF1) levels in epidermal cells indicating induction of damage to the DNA.	6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene	16-20	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	108-112	
17622315-8	2007	Treatment of DMBA-exposed animals with the liposomal formulation of DAS ensued in upregulation of p53wt and p21/Waf1, while levels of p53mut expression reduced down.	6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene	13-17	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	112-116	
16448747-5	2006	Our results showed that DAS administration leads to modulation of the DMBA-induced levels of p21/ras oncoprotein as early as 24h after the DMBA application, suggesting down-regulation of the p21/ras by DAS.	6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene	70-74	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	93-96	
16448747-5	2006	Our results showed that DAS administration leads to modulation of the DMBA-induced levels of p21/ras oncoprotein as early as 24h after the DMBA application, suggesting down-regulation of the p21/ras by DAS.	6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene	139-143	cyclin-dependent kinase inhibitor 1A (P21)	Mus musculus	93-96