PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17725531-9 2007 DMBA induced the expression of mutant-p53 and Bcl-2. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene 0-4 B cell leukemia/lymphoma 2 Mus musculus 46-51 9484776-8 1998 Keratinocytes from the HK1.bcl-2 mice were significantly more resistant to cell death induction by U.V.-B, DMBA, and TPA, compared to control keratinocytes. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene 107-111 B cell leukemia/lymphoma 2 Mus musculus 27-32 9484776-9 1998 Furthermore, papillomas developed at a significantly greater frequency and shorter latency in the HK1.bcl-2 mice compared to control littermates following initiation with DMBA and promotion with TPA. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene 171-175 B cell leukemia/lymphoma 2 Mus musculus 102-107 32519911-7 2021 The treatment with OA effectively suppressed the DMBA-initiated liver carcinogenesis via modulation of antioxidant status, induction of apoptosis and autophagy through modulating the expression of Caspase-3, Bcl-2 and Beclin-1, inhibiting angiogenesis (VEGF), proliferation (PCNA), and improved liver function and histological picture with a reduction in AFP level. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene 49-53 B cell leukemia/lymphoma 2 Mus musculus 208-213 18652568-9 2008 Similarly, DMBA induced over expression of Bcl-2 was also reversed by topical treatment of IP6. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene 11-15 B cell leukemia/lymphoma 2 Mus musculus 43-48 18652568-10 2008 In addition to the modulation of mt p53 and Bcl-2 expressions, IP6 brought the DMBA-inhibited activity of caspases back to the normal or induced it above the normal levels. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene 79-83 B cell leukemia/lymphoma 2 Mus musculus 44-49 17725531-12 2007 Similarly Bcl-2 overexpression by DMBA was also inhibited by topical treatment of Cag when given along with DMBA. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene 34-38 B cell leukemia/lymphoma 2 Mus musculus 10-15 17725531-12 2007 Similarly Bcl-2 overexpression by DMBA was also inhibited by topical treatment of Cag when given along with DMBA. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene 108-112 B cell leukemia/lymphoma 2 Mus musculus 10-15 17725531-13 2007 Inhibition of mutant-p53 and Bcl-2 expression by Cag in DMBA-exposed mouse skin might contribute to the apoptogenic effect possibly exerted by Cag while suppressing the tumor development. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene 56-60 B cell leukemia/lymphoma 2 Mus musculus 29-34 17250426-10 2006 An opposite trend was observed in DMBA induced antiapoptotic proteins expressions, survivin and bcl-2, which were significantly downregulated by DAS supplementation. 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene 34-38 B cell leukemia/lymphoma 2 Mus musculus 96-101