PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19675564-2	2009	Using a model of retinal ischemia, we showed that treatment with phosphatidylserine (PS) and phosphatidylcholine (PC) liposomes significantly reduced the expression of proinflammatory genes, including that of Il1b, Il6, Ccl2, Ccl5, Cxcl10, and Icam1, 24 h after reperfusion.	Phosphatidylcholines	93-112	intercellular adhesion molecule 1	Homo sapiens	244-249	
10837365-6	2000	The intracellular signaling pathway leading to enhanced expression appeared to involve activation of a phospholipase C that hydrolyzes phosphatidylcholine (PC-PLC) because D609, a specific PC-PLC inhibitor, attenuated TNF-alpha-induced increases in production of diacyl-glycerol (DAG), a hydrolysis product of PC-PLC, and also attenuated TNF-alpha enhancement of ICAM-1 surface and gene expression.	Phosphatidylcholines	135-154	intercellular adhesion molecule 1	Homo sapiens	363-369	
19594939-12	2009	The expression levels of IL-8, ICAM-1, IP-10, MCP-1, TNF-alpha and MMP-1 were significantly reduced after PC pre-treatment for at least two hours.	Phosphatidylcholines	106-108	intercellular adhesion molecule 1	Homo sapiens	31-37	
19114730-5	2009	Phosphatidylcholine hydroxide (a hydroxyl analog of PCOOH) also induced THP-1 cell adhesion to ICAM-1, whereas nonoxidized PC, sn-2 truncated PCs, and other hydroperoxide compounds did not affect the adhesion.	Phosphatidylcholines	52-54	intercellular adhesion molecule 1	Homo sapiens	95-101	
11483407-4	2001	Tyrosine kinase inhibitors (genistein or tyrphostin 23) or phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor (D 609) attenuated TNF-alpha-induced ICAM-1 expression.	Phosphatidylcholines	59-78	intercellular adhesion molecule 1	Homo sapiens	160-166	
11093788-2	2000	Tyrosine kinase inhibitors (genistein or tyrphostin 23) or phosphatidylcholine-specific phospholipase C inhibitor (D609) attenuated IL-1beta-induced ICAM-1 expression.	Phosphatidylcholines	59-78	intercellular adhesion molecule 1	Homo sapiens	149-155