PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26841664-8 2015 The higher is ratio cholesterol alcohol/phosphatidylcholines in mono-layer of lipoproteins of very low density the slower is lipolysis, formation of ligand lipoproteins of very low density and their absorption by cells under apoB-100-endocytosis. Phosphatidylcholines 40-60 apolipoprotein B Homo sapiens 225-233 16631150-4 2006 It is shown that the spectral peaks assigned to the methyl head groups of phosphatidylcholine and sphingomyelin in the (1)H spectra of LDL exhibit line broadening when otherwise free thiol groups of apoB are covalently modified by methanethiosulfonate spin label. Phosphatidylcholines 74-93 apolipoprotein B Homo sapiens 199-203 19778326-14 2010 CONCLUSION: This is the first report to show the presence of apolipoprotein B and apolipoprotein B- oxidized phosphatidylcholine complex, which correspond to LDL and OxLDL, respectively, in gingival crevicular fluid. Phosphatidylcholines 109-128 apolipoprotein B Homo sapiens 82-98 11369799-3 2001 Here we applied proton NMR spectroscopy to probe surface phospholipids phosphatidylcholine (PC) and sphingomyelin (SM) of LDL particles during proteolytic degradation of apolipoprotein B-100 (apoB-100). Phosphatidylcholines 71-90 apolipoprotein B Homo sapiens 170-190 11369799-3 2001 Here we applied proton NMR spectroscopy to probe surface phospholipids phosphatidylcholine (PC) and sphingomyelin (SM) of LDL particles during proteolytic degradation of apolipoprotein B-100 (apoB-100). Phosphatidylcholines 92-94 apolipoprotein B Homo sapiens 170-190 11369799-4 2001 Initiation of apoB-100 degradation was accompanied by the abruptly increased intensity of the choline -N(CH(3))(3) resonance of PC molecules, indicating disruption of their interactions with apoB-100. Phosphatidylcholines 128-130 apolipoprotein B Homo sapiens 14-22 8071599-7 1994 Phosphatidylcholine increased apoB synthesis and secretion without affecting the synthesis or secretion of apoA-I. Phosphatidylcholines 0-19 apolipoprotein B Homo sapiens 30-34 11082530-7 2000 A new molecular interaction model for the beta-sheet structure and phosphatidylcholine headgroups is introduced and an overall view of the tertiary structure of apolipoprotein B-100 in the LDL particles is presented. Phosphatidylcholines 67-86 apolipoprotein B Homo sapiens 161-181 9748733-4 1998 The objective of the present study was to assess how the fatty acid composition in plasma phosphatidyl choline affects the total and LDL cholesterol, triglyceride and apolipoprotein B concentrations in subjects with primary hyperlipoproteinaemia and dyslipidaemia. Phosphatidylcholines 90-110 apolipoprotein B Homo sapiens 167-183 9748733-10 1998 CONCLUSIONS: The submitted results indicate that the fatty acid concentrations of PC in plasma are significantly and markedly correlated with concentrations of total cholesterol, triglycerides, LDL-cholesterol and apolipoprotein B. Phosphatidylcholines 82-84 apolipoprotein B Homo sapiens 214-230 8670072-8 1996 Phosphatidylcholine also increased the basolateral secretion of apolipoprotein B (apoB) mass without altering apoB mRNA levels. Phosphatidylcholines 0-19 apolipoprotein B Homo sapiens 64-80 8670072-8 1996 Phosphatidylcholine also increased the basolateral secretion of apolipoprotein B (apoB) mass without altering apoB mRNA levels. Phosphatidylcholines 0-19 apolipoprotein B Homo sapiens 82-86 8670072-9 1996 Disruption of the Golgi apparatus by monensin or brefeldin A prevented the increase in apoB secretion by phosphatidylcholine. Phosphatidylcholines 105-124 apolipoprotein B Homo sapiens 87-91 8670072-10 1996 Compared with microsomes prepared from control cells, those from cells incubated with phosphatidylcholine contained more newly synthesized apoB. Phosphatidylcholines 86-105 apolipoprotein B Homo sapiens 139-143 8670072-12 1996 Thus in CaCo-2 cells incubated with phosphatidylcholine, the transport of apoB and triacylglycerols is increased whereas cholesteryl ester synthesis and secretion are decreased. Phosphatidylcholines 36-55 apolipoprotein B Homo sapiens 74-78 8820101-7 1996 The epitope of this antibody resides in oxidized products of phosphatidylcholine that can form complexes with polypeptides, including apolipoprotein B. Phosphatidylcholines 61-80 apolipoprotein B Homo sapiens 134-150 10073990-10 1999 Moreover, this phenomenon appears to result not only from the significantly elevated PC to free cholesterol ratio (1.54:1) in dense LDL particles (1.15:1 to 1.25:1 for other LDL subclasses) but also from their unique structural features, including a distinct apoB100 conformation, which may facilitate covalent bond formation between oxidized CE and apoB100. Phosphatidylcholines 85-87 apolipoprotein B Homo sapiens 259-266 10073990-10 1999 Moreover, this phenomenon appears to result not only from the significantly elevated PC to free cholesterol ratio (1.54:1) in dense LDL particles (1.15:1 to 1.25:1 for other LDL subclasses) but also from their unique structural features, including a distinct apoB100 conformation, which may facilitate covalent bond formation between oxidized CE and apoB100. Phosphatidylcholines 85-87 apolipoprotein B Homo sapiens 350-357 9885772-9 1998 In general, PC appears to promote the translocation of apo B from the cytosol to the lumen of the endoplasmic reticulum, a step that is crucial in the early stages of VLDL assembly. Phosphatidylcholines 12-14 apolipoprotein B Homo sapiens 55-60 8857918-1 1996 Triglycerides (TGs), cholesteryl esters (CEs), cholesterol, and phosphatidylcholine have been independently proposed as playing regulatory roles in apoB-100 secretion; the results depended on the cellular model used. Phosphatidylcholines 64-83 apolipoprotein B Homo sapiens 148-156 8071599-8 1994 Phosphatidylcholine also reversed the effect of A23187 on apoB secretion. Phosphatidylcholines 0-19 apolipoprotein B Homo sapiens 58-62 8071599-9 1994 When phosphatidylcholine was added to the basolateral medium, apoB secretion was not altered. Phosphatidylcholines 5-24 apolipoprotein B Homo sapiens 62-66 8071599-17 1994 Phosphatidylcholine, independent of triacylglycerol flux and independent of its hydrolysis, increases the secretion of apoB by increasing apoB synthesis. Phosphatidylcholines 0-19 apolipoprotein B Homo sapiens 119-123 8071599-17 1994 Phosphatidylcholine, independent of triacylglycerol flux and independent of its hydrolysis, increases the secretion of apoB by increasing apoB synthesis. Phosphatidylcholines 0-19 apolipoprotein B Homo sapiens 138-142 8071599-18 1994 Luminal phosphatidylcholine may play a role in apoB secretion in the intestine. Phosphatidylcholines 8-27 apolipoprotein B Homo sapiens 47-51 34419589-7 2021 Cellular phosphatidylcholine/phosphatidylethanolamine ratio was decreased only upon overexpression of the proteins, potentially contributing to altered ApoB100 assembly and secretion. Phosphatidylcholines 9-28 apolipoprotein B Homo sapiens 152-159 35203427-5 2022 A sandwich ELISA detecting oxidized phosphatidylcholine in association with apolipoprotein B-100 (oxPL/apoB) was applied to measure oxidized phospholipids in circulation. Phosphatidylcholines 36-55 apolipoprotein B Homo sapiens 76-96 35203427-5 2022 A sandwich ELISA detecting oxidized phosphatidylcholine in association with apolipoprotein B-100 (oxPL/apoB) was applied to measure oxidized phospholipids in circulation. Phosphatidylcholines 36-55 apolipoprotein B Homo sapiens 103-107 3707893-7 1986 There is a loss of about 20% of the intensity of the N(CH3)3 resonance from phosphatidylcholine and sphingomyelin molecules in the LDL spectrum; this is attributed to the presence of apolipoprotein B in the surface of LDL particles, which may immobilize some of the phospholipid polar groups. Phosphatidylcholines 76-95 apolipoprotein B Homo sapiens 183-199 31488158-2 2019 We hypothesized that serum PC, as a reflection of phospholipid metabolism, changes after RYGB, and that changes are related to weight loss and possibly to changes in glucose metabolism (reflected in the HbA1c-level) as well as to changes in serum Apo A1, Apo B and Apo B/Apo A1 ratio. Phosphatidylcholines 27-29 apolipoprotein B Homo sapiens 255-260 31488158-2 2019 We hypothesized that serum PC, as a reflection of phospholipid metabolism, changes after RYGB, and that changes are related to weight loss and possibly to changes in glucose metabolism (reflected in the HbA1c-level) as well as to changes in serum Apo A1, Apo B and Apo B/Apo A1 ratio. Phosphatidylcholines 27-29 apolipoprotein B Homo sapiens 265-270 30115754-9 2018 Thus, reduced de novo PC synthesis in Caco2 cells enhances TG storage in large LDs and inhibits apoB48 chylomicron secretion. Phosphatidylcholines 22-24 apolipoprotein B Homo sapiens 96-102