PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2219115-6 1990 3-Methylcholanthrene pretreatment increased and pretreatment with cobalt chloride and piperonyl butoxide decreased the hepatic covalent binding of 3HAA, indicating the involvement of cytochrome P450 in the formation of the 3HAA reactive metabolite. Piperonyl Butoxide 86-104 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 183-198 16162970-8 2005 Potent cytotoxic activity of ET-743 after 120 h treatment was observed, which could be increased in combination with the CYP inhibitors metyrapone (3A4), phenanthrene (substrate for 2E1, 3A4), piperonyl butoxide (3A), proadifen (2C9, 2E1, 3A4), ritonavir (3A4), and warfarin (2C9, 2C19). Piperonyl Butoxide 193-211 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 121-124 8386241-4 1993 Covalent binding required oxygen and NADPH, and was decreased by the nucleophile glutathione and by the cytochrome P-450 inhibitors SKF 525-A, piperonyl butoxide and troleandomycin (an inhibitor of the cytochrome P-450 3A subfamily). Piperonyl Butoxide 143-161 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 104-120 8386241-4 1993 Covalent binding required oxygen and NADPH, and was decreased by the nucleophile glutathione and by the cytochrome P-450 inhibitors SKF 525-A, piperonyl butoxide and troleandomycin (an inhibitor of the cytochrome P-450 3A subfamily). Piperonyl Butoxide 143-161 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 202-218 2703963-8 1989 Several cytochrome P-450 inhibitors [metyrapone, 8-methoxypsoralen, 2-(4,6-dichloro-biphenyloxy) ethylamine, alpha-naphthoflavone and cimetidine] decreased the biliary excretion of AA-GS, although SKF 525-A and piperonyl butoxide did not. Piperonyl Butoxide 211-229 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 8-24 3711591-1 1986 Effect of acute doses of technical grade of dichloro diphenyl trichloro ethane (DDT) and piperonyl butoxide (PB) on hepatic microsomal cytochrome P450 (Cyt. Piperonyl Butoxide 89-107 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 135-150 3711591-1 1986 Effect of acute doses of technical grade of dichloro diphenyl trichloro ethane (DDT) and piperonyl butoxide (PB) on hepatic microsomal cytochrome P450 (Cyt. Piperonyl Butoxide 109-111 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 135-150