PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35051489-3	2022	This study was to investigate the hypothesis that BBR treats depressive-like behavior by shifting the balance of the kynurenine (KYN)/serotonin (5-HT) pathway toward the 5-HT pathway through downregulated indoleamine 2,3-dioxygenase 1 (IDO1), monoamine oxidase A (MAOA) and upregulated dopamine decarboxylase (DDC) in hippocampus.	Berberine	50-53	dopa decarboxylase	Mus musculus	286-308	
35051489-3	2022	This study was to investigate the hypothesis that BBR treats depressive-like behavior by shifting the balance of the kynurenine (KYN)/serotonin (5-HT) pathway toward the 5-HT pathway through downregulated indoleamine 2,3-dioxygenase 1 (IDO1), monoamine oxidase A (MAOA) and upregulated dopamine decarboxylase (DDC) in hippocampus.	Berberine	50-53	dopa decarboxylase	Mus musculus	310-313	
35051489-13	2022	BBR treatment downregulated IDO1 and MAOA, upregulated DDC.	Berberine	0-3	dopa decarboxylase	Mus musculus	55-58