PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23086664-1	2012	Highly regioselective: An efficient synthesis of the imidazo[1,2-b]pyrazole core has been developed, and the first regioselective palladium-catalyzed direct arylation of the C-3 position is described (see scheme).	Palladium	130-139	complement C3	Homo sapiens	174-177	
26402033-2	2015	Based on mechanistic studies, the tandem reaction follows the sequence: palladium-catalyzed regioselective C-3 alkenylation/palladium-catalyzed C-2 alkenylation/thermal electrocyclization.	Palladium	72-81	complement C3	Homo sapiens	107-110	
26402033-2	2015	Based on mechanistic studies, the tandem reaction follows the sequence: palladium-catalyzed regioselective C-3 alkenylation/palladium-catalyzed C-2 alkenylation/thermal electrocyclization.	Palladium	124-133	complement C3	Homo sapiens	107-110	
25213659-1	2014	We describe a straightforward strategy for the synthesis of strongly fluorescent pyridoindoles by Pd-catalyzed oxidative annulations of internal alkynes with C-3 functionalized indoles through C H/N H bond activation in a one-pot tandem process.	Palladium	98-100	complement C3	Homo sapiens	158-161	
11667407-2	1996	The olefin undergoes two types of palladium-catalyzed reactions: (a) arylation to provide C-3 arylated derivatives and (b) competing double bond isomerization.	Palladium	34-43	complement C3	Homo sapiens	90-93	
32459097-0	2020	Palladium-Catalyzed C-2 and C-3 Dual C-H Functionalization of Indoles: Synthesis of Fluorinated Isocryptolepine Analogues.	Palladium	0-9	complement C3	Homo sapiens	28-31	
27346186-3	2016	The final route proceeds from 7-bromoindole by sequential palladium-catalysed couplings of an oxazole fragment at C-2, followed by a tyrosine fragment at C-3.	Palladium	58-67	complement C3	Homo sapiens	154-157	
25785825-1	2015	The palladium-catalyzed reaction of 2,3,3-trifluoroallyl esters with several types of amines afforded trifluoromethylenamines, which were formed by the addition of a nitrogen nucleophile at the C-2 position and the intramolecular construction of the trifluoromethyl group via the fluorine atom shift from the C-2 to the C-3 position.	Palladium	4-13	complement C3	Homo sapiens	320-323	
21332150-0	2011	Palladium-catalyzed oxidative C-H bond and C C double bond cleavage: C-3 acylation of indolizines with alpha,beta-unsaturated carboxylic acids.	Palladium	0-9	complement C3	Homo sapiens	69-72	
22530559-1	2012	Chiral 2-piperidinone compounds with various C-6 substituents were successfully synthesized via a Pd-catalyzed asymmetric 6-endo cyclization of dienamides, which were evidently activated by both N-p-toluenesulfonyl and C-3 ester substituents.	Palladium	98-100	complement C3	Homo sapiens	219-222	
21332150-1	2011	A novel palladium-catalyzed C-3 acylation of indolizines with alpha,beta-unsaturated carboxylic acids via C-H bond and C C double bond cleavage under oxidative conditions is described.	Palladium	8-17	complement C3	Homo sapiens	28-31	
16683785-0	2006	Palladium-catalyzed enantioselective C-3 allylation of 3-substituted-1H-indoles using trialkylboranes.	Palladium	0-9	complement C3	Homo sapiens	37-40	
20030386-5	2010	Starting from an arylated propargylic ether the three-component reaction led to a pentasubstituted 4-hydroxypyridine derivative that could also be employed in palladium-catalyzed processes at C-4 and at C-3 of the pyridine core.	Palladium	159-168	complement C3	Homo sapiens	203-206	
15926829-0	2005	Direct palladium-catalyzed C-2 and C-3 arylation of indoles: a mechanistic rationale for regioselectivity.	Palladium	7-16	complement C3	Homo sapiens	35-38	
15040747-1	2004	A highly effective protocol for palladium-catalyzed selective arylation and heteroarylation of indolizines at C-3 has been developed.	Palladium	32-41	complement C3	Homo sapiens	110-113