PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22235427-0 2011 Production of late IFN-alpha induced by plasma gamma-globulin fraction proteins and their metal complexes. Metals 90-95 interferon alpha 1 Homo sapiens 19-28 22235427-1 2011 Plasma gamma-globulin fraction proteins, copper and zinc cations, and metal complexes they form with human serum gamma-globulin induce the production of IFN-alpha by human blood cells throughout the periods of up to 72 h. Zinc cation-modified protein by 1.6 times (p<0.05) more actively induces late IFN-alpha than the control gamma-globulin; gamma-globulin-copper metal complex is 2-fold (p<0.002) more effective than the control protein. Metals 70-75 interferon alpha 1 Homo sapiens 153-162 22235427-1 2011 Plasma gamma-globulin fraction proteins, copper and zinc cations, and metal complexes they form with human serum gamma-globulin induce the production of IFN-alpha by human blood cells throughout the periods of up to 72 h. Zinc cation-modified protein by 1.6 times (p<0.05) more actively induces late IFN-alpha than the control gamma-globulin; gamma-globulin-copper metal complex is 2-fold (p<0.002) more effective than the control protein. Metals 70-75 interferon alpha 1 Homo sapiens 303-312 22235427-1 2011 Plasma gamma-globulin fraction proteins, copper and zinc cations, and metal complexes they form with human serum gamma-globulin induce the production of IFN-alpha by human blood cells throughout the periods of up to 72 h. Zinc cation-modified protein by 1.6 times (p<0.05) more actively induces late IFN-alpha than the control gamma-globulin; gamma-globulin-copper metal complex is 2-fold (p<0.002) more effective than the control protein. Metals 368-373 interferon alpha 1 Homo sapiens 153-162 19907752-1 2009 Interferon-alpha was detected in IFN pool produced by human leukocytes in the presence of gamma-globulin fraction proteins, copper and zinc cations, and metal-modified gamma-globulins. Metals 153-158 interferon alpha 1 Homo sapiens 33-36 19526099-1 2008 Plasma gamma-globulin fraction proteins, copper and zinc cations, and metal-modified gamma-globulins induce the production of IFN by human leukocytes. Metals 70-75 interferon alpha 1 Homo sapiens 126-129 6201571-4 1984 This was related to suppression of viral IFN induction by metal particles. Metals 58-63 interferon alpha 1 Homo sapiens 41-44 6201571-5 1984 Neuraminidase treatment of cell surface salioglycoproteins or pretreatment of chromium or manganese particles with sialic acid abrogated the adverse activity of metal particles on viral IFN induction. Metals 161-166 interferon alpha 1 Homo sapiens 186-189