PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32133426-3	2020	Herein, we use a tiered strategy employing both targeted biological assays and untargeted quantitative proteomics to elucidate the biological responses of human THP-1 derived macrophages across a library of metal/metal oxide ENMs, raised as priority ENMs for investigation by NIEHS"s Nanomaterial Health Implications Research (NHIR) program.	Metals	207-212	GLI family zinc finger 2	Homo sapiens	161-166	
32150886-0	2020	Comparison of Inflammatory Effects in THP-1 Monocytes and Macrophages after Exposure to Metal Ions.	Metals	88-93	GLI family zinc finger 2	Homo sapiens	38-43	
32150886-3	2020	To do this, the THP-1 cell line was used to analyze the effects of metal ions simultaneously in monocytes and differentiated macrophages.	Metals	67-72	GLI family zinc finger 2	Homo sapiens	16-21	
27528055-2	2017	We have evaluated the most promising compounds for their efficiency to a) intercept and scavenge free radicals, b) inhibit the metal ion (Cu2+)- induced LDL oxidation c) act intracellularly as antioxidants in THP-1 monocytes from a leukemic patient and d) inhibit the pro-inflammatory enzymes cyclooxygenase-1 (COX-1) and -2 (COX-2) in vitro.	Metals	127-132	GLI family zinc finger 2	Homo sapiens	209-214	
27973853-0	2017	Cytotoxic and Proinflammatory Effects of Metal-Based Nanoparticles on THP-1 Monocytes Characterized by Combined Proteomics Approaches.	Metals	41-46	GLI family zinc finger 2	Homo sapiens	70-75	
30516368-2	2019	We report here the first case of a luminescent metal organic framework based probe (ThP-1) for highly sensitive and selective self-calibrated sensing of Th4+ contamination in natural fresh water media with a notably facilitated detection procedure.	Metals	47-52	GLI family zinc finger 2	Homo sapiens	84-89	
9171001-0	1996	In vitro IL-1 beta and TNF-alpha release from THP-1 monocytes in response to metal ions.	Metals	77-82	GLI family zinc finger 2	Homo sapiens	46-51	
23053298-5	2013	The results indicate that integration of biological layers around a metal mesh core-regardless of its type-may reduce the evoked inflammatory responses by THP-1 monocyte-like cells.	Metals	68-73	GLI family zinc finger 2	Homo sapiens	155-160	
21377791-0	2011	Ubiquitous hazardous metal lead induces TNF-alpha in human phagocytic THP-1 cells: primary role of ERK 1/2.	Metals	21-26	GLI family zinc finger 2	Homo sapiens	70-75	
19895645-3	2009	Large Legionella deletion strains of the metal efflux genes were tested in human THP-1-derived macrophages and amoebal Acanthamoeba castellanii cells and were able to survive and replicate similar to the wild type, suggesting that they do not play a significant role within the intracellular environment.	Metals	41-46	GLI family zinc finger 2	Homo sapiens	81-86	
10547182-2	1999	Here, we explore the role of protein kinase C (PKC) in regulating transition metal reduction by each of these redox-active pathways, in human (THP-1) monocytes.	Metals	77-82	GLI family zinc finger 2	Homo sapiens	143-148	
10951376-4	2000	THP-1 human monocytes were exposed to the metal ions for up to 4 weeks.	Metals	42-47	GLI family zinc finger 2	Homo sapiens	0-5	
10888278-0	2000	Effect of dental metal ions on glutathione levels in THP-1 human monocytes.	Metals	17-22	GLI family zinc finger 2	Homo sapiens	53-58