PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30046785-2 2018 Herein, we report the effects of S100A8/S100A9 heterooligomer calprotectin (CP) and the S100B homodimer on metal-free and metal-bound amyloid-beta (Abeta; Abeta40 and Abeta42) aggregation in vitro. Metals 107-112 S100 calcium binding protein B Homo sapiens 88-93 30046785-2 2018 Herein, we report the effects of S100A8/S100A9 heterooligomer calprotectin (CP) and the S100B homodimer on metal-free and metal-bound amyloid-beta (Abeta; Abeta40 and Abeta42) aggregation in vitro. Metals 122-127 S100 calcium binding protein B Homo sapiens 88-93 30069254-2 2018 With S100beta protein being a metal binding brain-specific receptor for both extracellular and intracellular functions, a change in conformation due to the above-mentioned factors, can compromise their cellular functions and therefore result in several pathological conditions such as Alzheimer"s disease, Ischemic stroke, as well as Myocardial Infarction. Metals 30-35 S100 calcium binding protein B Homo sapiens 5-13 28539487-3 2017 Recombinant human NEF-sp demonstrates a divalent metal ion-dependent 3" 5" exoribonuclease activity. Metals 49-54 S100 calcium binding protein B Homo sapiens 18-21 29386995-0 2017 Zinc Binding to S100B Affords Regulation of Trace Metal Homeostasis and Excitotoxicity in the Brain. Metals 50-55 S100 calcium binding protein B Homo sapiens 16-21 29386995-5 2017 Here we report a novel role of S100B in trace metal homeostasis, in particular the regulation of zinc levels in the brain. Metals 46-51 S100 calcium binding protein B Homo sapiens 31-36 29386995-12 2017 We conclude that in addition to its known functions, S100B acts as sensor and regulator of elevated zinc levels in the brain and this metal-buffering activity is tied to a neuroprotective role. Metals 134-139 S100 calcium binding protein B Homo sapiens 53-58 27159591-0 2016 An Interplay of S-Nitrosylation and Metal Ion Binding for Astrocytic S100B Protein. Metals 36-41 S100 calcium binding protein B Homo sapiens 69-74 26726132-6 2017 A specific subset of the calcium sensor proteins (calmodulin, S100B, NCS-1, GCAP-1/2) exhibits metal-dependent binding of IL-11 with dissociation constants of 1-19 muM. Metals 95-100 S100 calcium binding protein B Homo sapiens 62-67 27430886-3 2016 Here we summarize current knowledge of S100 protein binding of Zn(2+), Cu(2+) and Mn(2+) ions, focusing on binding affinities, conformational changes that arise from metal binding, and the roles of transition metal binding in S100 protein function. Metals 166-171 S100 calcium binding protein B Homo sapiens 39-43 27430886-3 2016 Here we summarize current knowledge of S100 protein binding of Zn(2+), Cu(2+) and Mn(2+) ions, focusing on binding affinities, conformational changes that arise from metal binding, and the roles of transition metal binding in S100 protein function. Metals 209-214 S100 calcium binding protein B Homo sapiens 39-43 25451971-0 2014 S100beta in heavy metal-related child attention-deficit hyperactivity disorder in an informal e-waste recycling area. Metals 18-23 S100 calcium binding protein B Homo sapiens 0-8 26055713-4 2015 In this review, we focus on S100 proteins that exhibit antimicrobial properties through the process of metal limitation, termed nutritional immunity, and discuss several recent advances in our understanding of S100 protein-mediated metal sequestration at the site of infection. Metals 103-108 S100 calcium binding protein B Homo sapiens 28-32 25451971-10 2014 Serum S100beta levels were associated with heavy metal levels in blood, and certain behavioral abnormalities. Metals 49-54 S100 calcium binding protein B Homo sapiens 6-14 20858440-6 2010 The conformation of Nef was probed upon binding to Langmuir monolayers through the interaction of an N-terminal His tag with a synthetic metal-chelating lipid, which models one of the possible limiting cases for myr-Nef. Metals 137-142 S100 calcium binding protein B Homo sapiens 20-23 25251247-1 2014 A Nef reaction has been developed that is conducted under mildly basic conditions with molecular oxygen as an oxidant, without the need for metal additives. Metals 140-145 S100 calcium binding protein B Homo sapiens 2-5 22528103-4 2012 S100 proteins exhibit considerable structural plasticity, being able to exist as monomers or assemble into dimers, higher oligomers, and amyloids, frequently in a metal-dependent manner. Metals 163-168 S100 calcium binding protein B Homo sapiens 0-4 32569467-4 2020 The metal-free flavin/NOx/TEMPO catalytic cycles are uniquely compatible, especially compared to other Nef and NOx-generating processes, and reveal selectivity over flavin-catalyzed sulfoxide formation. Metals 4-9 S100 calcium binding protein B Homo sapiens 103-106 19930574-9 2009 Moreover, purification of Nef from agroinfiltrated tissue was achieved by a two-step immobilized metal ion affinity chromatography protocol with yields of 250 ng/g of fresh tissue. Metals 97-102 S100 calcium binding protein B Homo sapiens 26-29 18602402-0 2008 Divalent metal ion complexes of S100B in the absence and presence of pentamidine. Metals 9-14 S100 calcium binding protein B Homo sapiens 32-37 15590070-5 2004 The presented results provide a mechanistic basis for further studies of the function of S100 proteins in the control of redox-based and metal-based signal transduction. Metals 137-142 S100 calcium binding protein B Homo sapiens 89-93 12821199-0 2003 Two-step purification of His-tagged Nef protein in native condition using heparin and immobilized metal ion affinity chromatographies. Metals 98-103 S100 calcium binding protein B Homo sapiens 36-39 12821199-3 2003 A two-step procedure that includes heparin and immobilized metal ion affinity chromatographies (IMACs) was developed to purify His-tagged Nef (His(6)-Nef) expressed in bacteria in native condition. Metals 59-64 S100 calcium binding protein B Homo sapiens 138-141 12821199-3 2003 A two-step procedure that includes heparin and immobilized metal ion affinity chromatographies (IMACs) was developed to purify His-tagged Nef (His(6)-Nef) expressed in bacteria in native condition. Metals 59-64 S100 calcium binding protein B Homo sapiens 143-153 1419966-0 1992 Binding study of metal ions to S100 protein: 43Ca, 25Mg, 67Zn and 39K n.m.r. Metals 17-22 S100 calcium binding protein B Homo sapiens 31-35 2271488-5 1990 In contrast, the binding affinity of TRP to S100b protein in the presence and absence of metal ions was lower than to S100a and S100ao proteins. Metals 89-94 S100 calcium binding protein B Homo sapiens 44-49 31156365-6 2019 Recent evidence also suggests that metal-ligation by S100 proteins influences trace metal homeostasis in the brain, particularly of zinc, which is also a major deregulated process in AD. Metals 35-40 S100 calcium binding protein B Homo sapiens 53-57 31156365-6 2019 Recent evidence also suggests that metal-ligation by S100 proteins influences trace metal homeostasis in the brain, particularly of zinc, which is also a major deregulated process in AD. Metals 84-89 S100 calcium binding protein B Homo sapiens 53-57