PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14980935-4 2004 HES was found to inhibit lung neutrophil accumulation, cytokine-induced neutrophil chemoattractant protein, and NF-kappaB activation in parallel and to inhibit CD11b expression in a dose-dependent manner. Hydroxyethyl Starch Derivatives 0-3 nuclear factor kappa B subunit 1 Homo sapiens 112-121 14980935-5 2004 These findings demonstrate that HES has beneficial effects on capillary leak in acute lung injury and that the mechanisms underlying this action involve an antiinflammatory effect of HES, including inhibition of NF-kappaB activation. Hydroxyethyl Starch Derivatives 32-35 nuclear factor kappa B subunit 1 Homo sapiens 212-221 14980935-5 2004 These findings demonstrate that HES has beneficial effects on capillary leak in acute lung injury and that the mechanisms underlying this action involve an antiinflammatory effect of HES, including inhibition of NF-kappaB activation. Hydroxyethyl Starch Derivatives 183-186 nuclear factor kappa B subunit 1 Homo sapiens 212-221 14584760-2 2003 The present study tested the hypothesis that HES has effects on nuclear factor kappa B (NF-kappaB) activation and the expression of inflammatory mediators induced by lipopolysaccharide. Hydroxyethyl Starch Derivatives 45-48 nuclear factor kappa B subunit 1 Homo sapiens 88-97 14584760-6 2003 Treatment of rats with HES (3.75 and 7.5 ml/kg) prevented LPS-induced NF-kappaB activation, and inhibited, in a dose-related manner, LPS-induced TNF-alpha and CINC expression. Hydroxyethyl Starch Derivatives 23-26 nuclear factor kappa B subunit 1 Homo sapiens 70-79