PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18399119-1 2007 OBJECTIVE: To explore the protective effects of hydroxyethyl starch (HES)(130/0.4) against ischemia reperfusion injury of kidney and its impact on the expression of intercellular adhesion molecule-1 (ICAM-1). Hydroxyethyl Starch Derivatives 69-72 intercellular adhesion molecule 1 Rattus norvegicus 165-198 20451670-8 2010 Meanwhile, HES could significantly reduce TNF-alpha, IL-6, and ICAM-1 mRNA, inhibit NF-kappaB activation, and down-regulate TLR2 and TLR4 expression in the brain. Hydroxyethyl Starch Derivatives 11-14 intercellular adhesion molecule 1 Rattus norvegicus 63-69 18399119-1 2007 OBJECTIVE: To explore the protective effects of hydroxyethyl starch (HES)(130/0.4) against ischemia reperfusion injury of kidney and its impact on the expression of intercellular adhesion molecule-1 (ICAM-1). Hydroxyethyl Starch Derivatives 69-72 intercellular adhesion molecule 1 Rattus norvegicus 200-206 18399119-11 2007 CONCLUSION: Infusion of 10-20 ml/kg HES (130/0.4) significantly alleviates the ischemia-reperfusion injury, probably by reducing the ICAM-1 expression. Hydroxyethyl Starch Derivatives 36-39 intercellular adhesion molecule 1 Rattus norvegicus 133-139