PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11430463-0	2001	NTE-122, an acyl-coa:cholesterol acyltransferase inhibitor, prevents the progression of atherogenesis in cholesterol-fed rabbits.	NTE 122	0-7	sterol O-acyltransferase 1	Oryctolagus cuniculus	12-48	
9869270-0	1998	Cholesterol-lowering effects of NTE-122, a novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, on cholesterol diet-fed rats and rabbits.	NTE 122	32-39	sterol O-acyltransferase 1	Oryctolagus cuniculus	49-85	
9869270-0	1998	Cholesterol-lowering effects of NTE-122, a novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, on cholesterol diet-fed rats and rabbits.	NTE 122	32-39	sterol O-acyltransferase 1	Oryctolagus cuniculus	87-91	
9869270-1	1998	Pharmacological characterization of NTE-122 (trans-1,4-bis[[1-cyclohexyl-3-(4-dimethylamino phenyl)ureido]methyl]cyclohexane), a novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, was performed with both in vitro and in vivo assay systems.	NTE 122	36-43	sterol O-acyltransferase 1	Oryctolagus cuniculus	135-171	
9869270-1	1998	Pharmacological characterization of NTE-122 (trans-1,4-bis[[1-cyclohexyl-3-(4-dimethylamino phenyl)ureido]methyl]cyclohexane), a novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, was performed with both in vitro and in vivo assay systems.	NTE 122	36-43	sterol O-acyltransferase 1	Oryctolagus cuniculus	173-177	
9869270-1	1998	Pharmacological characterization of NTE-122 (trans-1,4-bis[[1-cyclohexyl-3-(4-dimethylamino phenyl)ureido]methyl]cyclohexane), a novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, was performed with both in vitro and in vivo assay systems.	NTE 122	45-124	sterol O-acyltransferase 1	Oryctolagus cuniculus	135-171	
9869270-1	1998	Pharmacological characterization of NTE-122 (trans-1,4-bis[[1-cyclohexyl-3-(4-dimethylamino phenyl)ureido]methyl]cyclohexane), a novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, was performed with both in vitro and in vivo assay systems.	NTE 122	45-124	sterol O-acyltransferase 1	Oryctolagus cuniculus	173-177	
9869270-2	1998	NTE-122 inhibited microsomal ACAT activities of various tissues (liver of rabbit and rat, small intestine of rabbit and rat, and aorta of rabbit) and cultured cells (HepG2 and CaCo-2), with IC50 values from 1.2 to 9.6 nM.	NTE 122	0-7	sterol O-acyltransferase 1	Oryctolagus cuniculus	29-33	
9869270-3	1998	The inhibition mode of NTE-122 was competitive for HepG2 ACAT.	NTE 122	23-30	sterol O-acyltransferase 1	Oryctolagus cuniculus	57-61	
9869270-7	1998	These results indicate that NTE-122 is a potent, selective and competitive inhibitor of ACAT, making it a worth while therapeutic agent for hypercholesterolemia and atherosclerosis.	NTE 122	28-35	sterol O-acyltransferase 1	Oryctolagus cuniculus	88-92