PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30402883-8 2019 Therefore, it appears that perturbation in iron homoeostasis has essential role in HLA-DR mediated antigen presentation and innate armoury by downregulating iNOS as well as altering IFN-gamma, IL-6 and IL-10 profiles. Iron 43-47 interleukin 10 Homo sapiens 202-207 32335809-7 2020 Iron overload is also associated with increased IL-10 and lower CCL11 levels, but these alterations are not significantly associated with depression. Iron 0-4 interleukin 10 Homo sapiens 48-53 30994016-0 2019 Potential role of MRN-100, an iron-based compound, in upregulating production of cytokine IL-10 in human dendritic cells to promote an anti-inflammatory response in vitro. Iron 30-34 interleukin 10 Homo sapiens 90-95 26185605-5 2015 Some of the suggested pathways are via transcription modulator of hepcidin (STAT3); ferroportin 1 expression on the cells involved in iron transport; transmembrane protease 6 enzyme; and pro-inflammatory cytokines, interleukin (IL)-1, IL-6, tumor necrosis factor-alpha and IL-10. Iron 134-138 interleukin 10 Homo sapiens 273-278 29872401-0 2018 Excessive Iron Availability Caused by Disorders of Interleukin-10 and Interleukin-22 Contributes to High Altitude Polycythemia. Iron 10-14 interleukin 10 Homo sapiens 51-65 29872401-9 2018 Conclusion: These data demonstrated, for the first time, that an excess of obtainable iron caused by disordered IL-10 and IL-22 was involved in the pathogenesis of some HAPC patients. Iron 86-90 interleukin 10 Homo sapiens 112-117 29771935-5 2018 Under LPS-induced inflammatory conditions, low iron diet exacerbated the proinflammatory response, while the IL-12/IL-10 balance decreased with iron-rich diet, thus polarizing toward type 2 response. Iron 144-148 interleukin 10 Homo sapiens 115-120 25194615-12 2014 CONCLUSIONS: Our results raise the possibility that IL-10 may play a role in iron homeostasis. Iron 77-81 interleukin 10 Homo sapiens 52-57 21413929-5 2011 Further secretory IL-10 level was significantly increased (P<0.001) or decreased (P<0.001) in response to iron supplementation [FAC (ferric ammonium citrate)] and depletion [DFO (deferoxamine)], respectively. Iron 112-116 interleukin 10 Homo sapiens 18-23 24520384-11 2014 The results are consistent with a role for IL-10 in modulating iron metabolism during acute phase of infection. Iron 63-67 interleukin 10 Homo sapiens 43-48 23580874-0 2013 Comments on: "Impact of iron overload on interleukin-10 levels, biochemical parameters and oxidative stress in patients with sickle cell anemia". Iron 24-28 interleukin 10 Homo sapiens 41-55 23580881-0 2013 Impact of iron overload on interleukin-10 levels, biochemical parameters and oxidative stress in patients with sickle cell anemia. Iron 10-14 interleukin 10 Homo sapiens 27-41 23580881-1 2013 OBJECTIVE: The aim of this study was to evaluate the impact of iron overload on the profile of interleukin-10 levels, biochemical parameters and oxidative stress in sickle cell anemia patients. Iron 63-67 interleukin 10 Homo sapiens 95-109 23580881-10 2013 The Iron overload Group showed lower interleukin-10 levels and catalase activity and higher nitrite and malondialdehyde levels compared with the Non-iron overload Group. Iron 4-8 interleukin 10 Homo sapiens 37-51 21547258-5 2011 Anti-inflammatory cytokine levels were normal, except for Il-10, supporting previous indications that Il-10 contributes to reducing bioavailable iron. Iron 145-149 interleukin 10 Homo sapiens 102-107 15853921-4 2005 Furthermore, IL-10 mRNA was higher in parasite blood smear-positive children than in blood smear-negative children irrespective of their iron status. Iron 137-141 interleukin 10 Homo sapiens 13-18 16793032-6 2006 CONCLUSION: The IHD patients with low serum iron were associated with a pro-inflammatory state, such as increased TNF-alpha, IL-6, and hsCRP; increased anti-inflammatory activities, such as increased IL-10; decreased cardiac protective factor, such as decreased IGF-I. Iron 44-48 interleukin 10 Homo sapiens 200-205 15507399-3 2004 Addition of iron to the culture medium did not affect the secretion of IL-2 and IL-1beta, but caused an increase in IL-6, IL-10, and TNF-alpha production. Iron 12-16 interleukin 10 Homo sapiens 122-127 12165551-4 2002 Patients receiving higher doses of IL-10 developed anemia and presented with a dose-dependent increase of ferritin and soluble transferrin receptor levels, an indicator of iron restriction to erythroid progenitor cells. Iron 172-176 interleukin 10 Homo sapiens 35-40 12522003-4 2003 Combined treatment of cells with interferon-gamma (IFN-gamma) and lipopolysaccharide (LPS) reduced TfR mRNA levels, surface expression, and iron uptake, and these effects were reversed by interleukin-10 (IL-10), thus stimulating TfR-mediated iron acquisition. Iron 140-144 interleukin 10 Homo sapiens 188-202 12522003-4 2003 Combined treatment of cells with interferon-gamma (IFN-gamma) and lipopolysaccharide (LPS) reduced TfR mRNA levels, surface expression, and iron uptake, and these effects were reversed by interleukin-10 (IL-10), thus stimulating TfR-mediated iron acquisition. Iron 242-246 interleukin 10 Homo sapiens 188-202 12522003-4 2003 Combined treatment of cells with interferon-gamma (IFN-gamma) and lipopolysaccharide (LPS) reduced TfR mRNA levels, surface expression, and iron uptake, and these effects were reversed by interleukin-10 (IL-10), thus stimulating TfR-mediated iron acquisition. Iron 242-246 interleukin 10 Homo sapiens 204-209 12522003-9 2003 Opposite, the anti-inflammatory cytokine IL-10 stimulates TfR-mediated iron uptake into activated monocytes. Iron 71-75 interleukin 10 Homo sapiens 41-46 12165551-7 2002 Our data demonstrate that IL-10 causes anemia in patients with inflammatory bowel disease which may be referred to the induction of imbalances in iron homeostasis by the cytokine, leading to hyperferritinemia and limited iron availability to erythroid progenitor cells, a condition typically seen in the anemia of chronic inflammation. Iron 146-150 interleukin 10 Homo sapiens 26-31 12165551-7 2002 Our data demonstrate that IL-10 causes anemia in patients with inflammatory bowel disease which may be referred to the induction of imbalances in iron homeostasis by the cytokine, leading to hyperferritinemia and limited iron availability to erythroid progenitor cells, a condition typically seen in the anemia of chronic inflammation. Iron 221-225 interleukin 10 Homo sapiens 26-31 34536483-6 2022 Furthermore, TLR4-induced, auto-/paracrine IL-10/IL-10R activation promoted expression of hepcidin, the master regulator of iron metabolism, resulting in intracellular iron sequestration. Iron 124-128 interleukin 10 Homo sapiens 43-48 34536483-6 2022 Furthermore, TLR4-induced, auto-/paracrine IL-10/IL-10R activation promoted expression of hepcidin, the master regulator of iron metabolism, resulting in intracellular iron sequestration. Iron 168-172 interleukin 10 Homo sapiens 43-48