PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22093255-5	2012	RESULTS: Hypoxia and the non-iron binding hypoxia mimetic dimethyl oxallyl glycine (DMOG) inhibited TNFalpha-mediated induction of VCAM-1.	Iron	29-33	vascular cell adhesion molecule 1	Homo sapiens	131-137	
33765133-3	2021	Here, we show that the absence of PPARgamma affects neonatal development and VCAM-1 expression of splenic iron-recycling red pulp macrophages (RPMs) and bone marrow erythroblastic island macrophages (EIMs).	Iron	106-110	vascular cell adhesion molecule 1	Homo sapiens	77-83	
24722448-3	2014	We found that expression levels of intracellular cell adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) and adhesion of U937 cells increased in iron-treated human aortic endothelial cells through upregulated NADPH oxidase (NOx) and NF-kappaB signaling.	Iron	170-174	vascular cell adhesion molecule 1	Homo sapiens	87-120	
24722448-3	2014	We found that expression levels of intracellular cell adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) and adhesion of U937 cells increased in iron-treated human aortic endothelial cells through upregulated NADPH oxidase (NOx) and NF-kappaB signaling.	Iron	170-174	vascular cell adhesion molecule 1	Homo sapiens	122-128	
22093255-1	2012	BACKGROUND: We previously reported that iron chelators inhibit TNFalpha-mediated induction of VCAM-1 in human dermal microvascular endothelial cells.	Iron	40-44	vascular cell adhesion molecule 1	Homo sapiens	94-100	
22093255-2	2012	We hypothesized that iron chelators mediate inhibition of VCAM-1 via inhibition of iron-dependent enzymes such as those involved with oxygen sensing and that similar inhibition may be observed with agents which simulate hypoxia.	Iron	21-25	vascular cell adhesion molecule 1	Homo sapiens	58-64	
22093255-2	2012	We hypothesized that iron chelators mediate inhibition of VCAM-1 via inhibition of iron-dependent enzymes such as those involved with oxygen sensing and that similar inhibition may be observed with agents which simulate hypoxia.	Iron	83-87	vascular cell adhesion molecule 1	Homo sapiens	58-64	
22093255-8	2012	CONCLUSION: Iron chelators, non-metal binding hypoxia mimetics, and hypoxia all inhibit TNFalpha-mediated VCAM-1 expression.	Iron	12-16	vascular cell adhesion molecule 1	Homo sapiens	106-112	
14708635-0	2003	Inhibition of vascular cell adhesion molecule-1 expression in human dermal microvascular endothelial cells by iron chelators.	Iron	110-114	vascular cell adhesion molecule 1	Homo sapiens	14-47	
20039148-1	2010	The present study was aimed to determine the effect of iron supplementation on levels of soluble intercellular adhesion molecule-1 (sICAM-1) and soluble vascular cell adhesion molecule-1 (sVCAM-1) in patients with iron deficiency anemia (IDA).	Iron	55-59	vascular cell adhesion molecule 1	Homo sapiens	153-186	
17962718-0	2008	Expression of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in human endometrial stromal and epithelial cells is regulated by interferon-gamma but not iron.	Iron	177-181	vascular cell adhesion molecule 1	Homo sapiens	52-85	
17962718-3	2008	The purpose of this study was to investigate iron incorporation by human endometrial cells and to test whether iron may stimulate expression of intercellular adhesion molecule (ICAM)-1 and vascular cell adhesion molecule (VCAM)-1.	Iron	111-115	vascular cell adhesion molecule 1	Homo sapiens	189-229	
12713595-0	2003	Iron chelators inhibit VCAM-1 expression in human dermal microvascular endothelial cells.	Iron	0-4	vascular cell adhesion molecule 1	Homo sapiens	23-29	
12713595-3	2003	The iron chelators dipyridyl (DP) and desferoxamine (DFO) inhibited VCAM-1 protein and mRNA induction in a concentration- and time-dependent manner.	Iron	4-8	vascular cell adhesion molecule 1	Homo sapiens	68-74	
12713595-4	2003	The induction of VCAM-1 was not inhibited by nonmetal binding reactive oxygen species (ROS) scavengers, implying a direct effect of iron in the expression of these adhesion molecules.	Iron	132-136	vascular cell adhesion molecule 1	Homo sapiens	17-23	
12713595-5	2003	The effect of iron was mediated at the level of gene transcription since pretreatment with DP abrogated the TNF alpha-mediated up-regulation of VCAM-1 heterogeneous nuclear RNA.	Iron	14-18	vascular cell adhesion molecule 1	Homo sapiens	144-150	
12713595-10	2003	These data suggest that iron plays a critical role in TNF alpha mediated VCAM-1 induction in HDMEC, and the target for iron effects may be IRF-1, NF-kappa B, and potentially chromatin remodeling.	Iron	24-28	vascular cell adhesion molecule 1	Homo sapiens	73-79