PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25703232-8	2015	We have demonstrated an interaction between the mutant huntingtin gene and iron supplementation in neonatal HD mice.	Iron	75-79	huntingtin	Mus musculus	55-65	
30002810-0	2018	Mutant huntingtin induces iron overload via up-regulating IRP1 in Huntington"s disease.	Iron	26-30	huntingtin	Mus musculus	7-17	
30002810-9	2018	Conclusion: We conclude that mutant huntingtin may cause abnormal iron homeostatic pathways by increasing IRP1 expression in Huntington"s disease, suggesting potential therapeutic target.	Iron	66-70	huntingtin	Mus musculus	36-46	
28715425-0	2017	Elimination of huntingtin in the adult mouse leads to progressive behavioral deficits, bilateral thalamic calcification, and altered brain iron homeostasis.	Iron	139-143	huntingtin	Mus musculus	15-25	
28715425-7	2017	Here we show that elimination of Htt expression in the adult mouse results in behavioral deficits, progressive neuropathological changes including bilateral thalamic calcification, and altered brain iron homeostasis.	Iron	199-203	huntingtin	Mus musculus	33-36	
25063332-1	2012	BACKGROUND: There is evidence that interaction with biologically important metals, particularly copper and iron, contributes to the pathological aggregation and toxicity of the mutant huntingtin protein in HD.	Iron	107-111	huntingtin	Mus musculus	184-194