PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28068628-0 2017 Epoxy clerodane diterpene inhibits MCF-7 human breast cancer cell growth by regulating the expression of the functional apoptotic genes Cdkn2A, Rb1, mdm2 and p53. Diterpenes 16-25 tumor protein p53 Homo sapiens 158-161 29644528-0 2018 A novel, semi-synthetic diterpenoid 16(R and S)-phenylamino-cleroda-3,13(14), Z-dien-15,16 olide (PGEA-AN) inhibits the growth and cell survival of human neuroblastoma cell line SH-SY5Y by modulating P53 pathway. Diterpenes 24-35 tumor protein p53 Homo sapiens 200-203 26939786-11 2016 Thus, for the first time, these data highlighted the potential use of the diterpene in the sensitization of GBM cells to chemotherapy through a direct re-activation of p53 pathway. Diterpenes 74-83 tumor protein p53 Homo sapiens 168-171 21620827-0 2011 The labdane diterpene sclareol (labd-14-ene-8, 13-diol) induces apoptosis in human tumor cell lines and suppression of tumor growth in vivo via a p53-independent mechanism of action. Diterpenes 12-21 tumor protein p53 Homo sapiens 146-149