PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23859780-0 2013 Cembrane diterpenoids from the soft coral Sarcophyton trocheliophorum Marenzeller as a new class of PTP1B inhibitors. Diterpenes 9-21 protein tyrosine phosphatase non-receptor type 1 Homo sapiens 100-105 30739823-3 2019 Recently, a number of new grayanane diterpenoids with unprecedented carbon skeletons have been obtained from plants of the Ericaceae family, and they exhibit diverse biological properties, such as agalgesic, antinociceptive, anticancer, antiviral, antifeedant, insecticidal, toxicity, and PTP1B. Diterpenes 36-48 protein tyrosine phosphatase non-receptor type 1 Homo sapiens 289-294 26960032-8 2016 This is the first report of serrulatane-type diterpenoids as potential alpha-glucosidase and/or PTP1B inhibitors. Diterpenes 45-57 protein tyrosine phosphatase non-receptor type 1 Homo sapiens 96-101 23859780-4 2013 This is the first report on the anti-PTP1B activity of cembrane diterpenoids. Diterpenes 64-76 protein tyrosine phosphatase non-receptor type 1 Homo sapiens 37-42 23141910-1 2012 In the course of ongoing research on protein tyrosine phosphatase 1B (PTP1B) inhibitory compounds from Antarctic lichens, four new diterpene furanoids, hueafuranoids A-D (1-4) have been isolated from the MeOH extract of Antarctic lichen Huea sp. Diterpenes 131-140 protein tyrosine phosphatase non-receptor type 1 Homo sapiens 37-68 23141910-1 2012 In the course of ongoing research on protein tyrosine phosphatase 1B (PTP1B) inhibitory compounds from Antarctic lichens, four new diterpene furanoids, hueafuranoids A-D (1-4) have been isolated from the MeOH extract of Antarctic lichen Huea sp. Diterpenes 131-140 protein tyrosine phosphatase non-receptor type 1 Homo sapiens 70-75 23141910-5 2012 The kinetic analysis of PTP1B inhibition by hueafuranoid A (1) suggested that the diterpene furanoids encountered in this study inhibited PTP1B activity in a non-competitive manner. Diterpenes 82-91 protein tyrosine phosphatase non-receptor type 1 Homo sapiens 24-29 23141910-5 2012 The kinetic analysis of PTP1B inhibition by hueafuranoid A (1) suggested that the diterpene furanoids encountered in this study inhibited PTP1B activity in a non-competitive manner. Diterpenes 82-91 protein tyrosine phosphatase non-receptor type 1 Homo sapiens 138-143