PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26186245-0 2015 Diterpenoids from aerial parts of Flickingeria fimbriata and their nuclear factor-kappaB inhibitory activities. Diterpenes 0-12 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 67-88 27154204-5 2016 Consistent with this result, DT pre-treatment inhibited nuclear factor kappaB (NF-kappaB) nuclear translocation, by interfering with IkappaBalpha phosphorylation, and consequently NF-kappaB transcriptional activity in endothelium activated by LPS or TNF-alpha. Diterpenes 29-31 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 71-77 27154204-5 2016 Consistent with this result, DT pre-treatment inhibited nuclear factor kappaB (NF-kappaB) nuclear translocation, by interfering with IkappaBalpha phosphorylation, and consequently NF-kappaB transcriptional activity in endothelium activated by LPS or TNF-alpha. Diterpenes 29-31 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 79-88 27154204-5 2016 Consistent with this result, DT pre-treatment inhibited nuclear factor kappaB (NF-kappaB) nuclear translocation, by interfering with IkappaBalpha phosphorylation, and consequently NF-kappaB transcriptional activity in endothelium activated by LPS or TNF-alpha. Diterpenes 29-31 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 180-189 17338565-0 2007 Kaurane diterpenoids from Isodon excisus inhibit LPS-induced NF-kappaB activation and NO production in macrophage RAW264.7 cells. Diterpenes 8-20 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 61-70 11278990-4 2001 These diterpenes inhibit NF-kappaB and IkappaB kinase (IKK) activation in vivo but failed to affect in vitro the function of NF-kappaB, the phosphorylation and targeting of IkappaBalpha, and the activity of IKK-2. Diterpenes 6-16 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 25-34 11278990-5 2001 Transient expression of NF-kappaB-inducing kinase (NIK) activated the IKK complex and NF-kappaB, a process that was inhibited by kaurenes, indicating that the inhibition of NIK was one of the targets of these diterpenes. Diterpenes 209-219 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 24-33 11488452-0 2001 Kaurane diterpenes from Isodon japonicus inhibit nitric oxide and prostaglandin E2 production and NF-kappaB activation in LPS-stimulated macrophage RAW264.7 cells. Diterpenes 8-18 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 98-107 11488452-5 2001 These results suggest that kaurane diterpenes could exert their inhibitory effects on the production of NO and PGE2 through the suppression of NF-kappaB activation, and be partially responsible for the anti-inflammatory activities of the genus Isodon. Diterpenes 35-45 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 143-152