PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22922340-0	2012	Lobolide, a diterpene, blockades the NF-kappaB pathway and p38 and ERK MAPK activity in macrophages in vitro.	Diterpenes	12-21	nuclear factor kappa B subunit 1	Homo sapiens	37-46	
26704389-3	2016	Oridonin is a diterpenoid isolated from Rabdosia rubescens that can block the NF-kappaB signaling cascades.	Diterpenes	14-25	nuclear factor kappa B subunit 1	Homo sapiens	81-87	
25447154-5	2015	A large number of targets of diterpenes have been identified in cancer cells including NF-kappaB, STAT3, Bcl-xL, beta-catenin, cytochrome C and caspases.	Diterpenes	29-39	nuclear factor kappa B subunit 1	Homo sapiens	87-96	
22922340-2	2012	The aim of this study was to characterize lobolide, a cembrane diterpene, as a drug candidate targeting the NF-kappaB signaling pathway.	Diterpenes	63-72	nuclear factor kappa B subunit 1	Homo sapiens	108-117	
19275691-5	2009	In the present review, molecular basis of the anti-inflammatory action of diterpenoids is presented with special emphasis on their ability to modulate critical cell signaling pathways involved in the inflammatory response of the body such as nuclear transcription factor-kappaB (NF-kappaB) activation.	Diterpenes	74-86	nuclear factor kappa B subunit 1	Homo sapiens	242-277	
20594187-8	2010	Triptolide (diterpenoid triepoxyde), a purified component of a traditional Chinese medicine, extracted from a shrub-like vine named Trypterygium wilfordii Hook F (TWHF) inhibits transcriptional activation of NF-kappaB and downregulates the expression of various NF-kappaB-regulated genes.	Diterpenes	12-23	nuclear factor kappa B subunit 1	Homo sapiens	208-217	
20594187-8	2010	Triptolide (diterpenoid triepoxyde), a purified component of a traditional Chinese medicine, extracted from a shrub-like vine named Trypterygium wilfordii Hook F (TWHF) inhibits transcriptional activation of NF-kappaB and downregulates the expression of various NF-kappaB-regulated genes.	Diterpenes	12-23	nuclear factor kappa B subunit 1	Homo sapiens	262-271	
19275691-5	2009	In the present review, molecular basis of the anti-inflammatory action of diterpenoids is presented with special emphasis on their ability to modulate critical cell signaling pathways involved in the inflammatory response of the body such as nuclear transcription factor-kappaB (NF-kappaB) activation.	Diterpenes	74-86	nuclear factor kappa B subunit 1	Homo sapiens	279-288	
19275691-8	2009	Hence, this article also introduces our recently elucidated findings about the potential of labdane diterpenoids as anti-inflammatory agents due to their ability to inhibit NF-kappaB.	Diterpenes	100-112	nuclear factor kappa B subunit 1	Homo sapiens	173-182	
16176802-0	2005	Differential control of growth, cell cycle progression, and expression of NF-kappaB in human breast cancer cells MCF-7, MCF-10A, and MDA-MB-231 by ponicidin and oridonin, diterpenoids from the chinese herb Rabdosia rubescens.	Diterpenes	171-183	nuclear factor kappa B subunit 1	Homo sapiens	74-83	
11877450-0	2002	Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes.	Diterpenes	8-17	nuclear factor kappa B subunit 1	Homo sapiens	42-52	
11877450-0	2002	Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes.	Diterpenes	8-17	nuclear factor kappa B subunit 1	Homo sapiens	103-106	
11877450-0	2002	Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes.	Diterpenes	8-17	nuclear factor kappa B subunit 1	Homo sapiens	150-160	
11877450-2	2002	We have previously shown that kamebakaurin and other three kaurane diterpenes selectively inhibit activation of transcription factor NF-kappaB, a central mediator of apoptosis and immune responses.	Diterpenes	67-77	nuclear factor kappa B subunit 1	Homo sapiens	133-142	
11999122-6	2002	A large number of compounds are currently known as NF-kappaB modulators and include the isoprenoids, most notably kaurene diterpenoids and members of the sesquiterpene lactones class, several phenolics including curcumin and flavonoids such as silybin.	Diterpenes	122-134	nuclear factor kappa B subunit 1	Homo sapiens	51-60