PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30154948-5	2018	Pretreatment with the H2S donor NaHS reduced autophagy and apoptosis levels in the ischemic myocardium and alleviated the regional inflammation response in the cardiac tissues of SOD1 KO mice.	Hydrogen Sulfide	22-25	superoxide dismutase 1	Homo sapiens	179-183	
31842297-3	2019	Previously, we reported that SOD is also a sulfide oxidase catalyzing the oxidation of hydrogen sulfide (H2S) to hydrogen persulfide (H2S2) and longer-chain polysulfides (H2Sn, n = 3-7).	Hydrogen Sulfide	87-103	superoxide dismutase 1	Homo sapiens	29-32	
31842297-0	2019	Manganese Porphyrin-Based SOD Mimetics Produce Polysulfides from Hydrogen Sulfide.	Hydrogen Sulfide	65-81	superoxide dismutase 1	Homo sapiens	26-29	
29220697-9	2018	Manganese SOD also catalyzed H2S oxidation to form polysulfides, but did not metabolize polysulfides indicating common attributes of these SODs.	Hydrogen Sulfide	29-32	superoxide dismutase 1	Homo sapiens	10-13	
29220697-0	2018	Metabolism of hydrogen sulfide (H2S) and Production of Reactive Sulfur Species (RSS) by superoxide dismutase.	Hydrogen Sulfide	14-30	superoxide dismutase 1	Homo sapiens	88-108	
29220697-4	2018	H2S was concentration- and oxygen-dependently oxidized by 1muM SOD to polysulfides (mainly H2S2, and to a lesser extent H2S3 and H2S5) with an EC50 of approximately 380muM H2S.	Hydrogen Sulfide	91-94	superoxide dismutase 1	Homo sapiens	63-66	
29220697-5	2018	H2S concentrations > 750muM inhibited SOD oxidation (IC50 = 1.25mM) with complete inhibition when H2S > 1.75mM.	Hydrogen Sulfide	0-3	superoxide dismutase 1	Homo sapiens	41-44	
29220697-7	2018	SOD oxidation preferred dissolved H2S over hydrosulfide anion (HS-), whereas HS- inhibited polysulfide production.	Hydrogen Sulfide	34-37	superoxide dismutase 1	Homo sapiens	0-3	
29220697-3	2018	Here we examined RSS metabolism by Cu/Zn superoxide dismutase (SOD) using amperometric electrodes for dissolved H2S, a polysulfide-specific fluorescent probe (SSP4), and mass spectrometry to identify specific polysulfides (H2S2-H2S5).	Hydrogen Sulfide	112-115	superoxide dismutase 1	Homo sapiens	63-66	
29220697-10	2018	These experiments suggest that, unlike the well-known SOD-mediated dismutation of two O2 - to form H2O2 and O2, SOD catalyzes a reaction using H2S and O2 to form persulfide.	Hydrogen Sulfide	143-146	superoxide dismutase 1	Homo sapiens	54-57	
29220697-4	2018	H2S was concentration- and oxygen-dependently oxidized by 1muM SOD to polysulfides (mainly H2S2, and to a lesser extent H2S3 and H2S5) with an EC50 of approximately 380muM H2S.	Hydrogen Sulfide	0-3	superoxide dismutase 1	Homo sapiens	63-66	
29220697-10	2018	These experiments suggest that, unlike the well-known SOD-mediated dismutation of two O2 - to form H2O2 and O2, SOD catalyzes a reaction using H2S and O2 to form persulfide.	Hydrogen Sulfide	143-146	superoxide dismutase 1	Homo sapiens	112-115	
29220697-12	2018	It is also possible that H2S (or polysulfides) interact/react with SOD cysteines to affect catalytic activity or to directly contribute to sulfide metabolism.	Hydrogen Sulfide	25-28	superoxide dismutase 1	Homo sapiens	67-70	
29220697-13	2018	Our studies suggest that H2S metabolism by SOD may have been an ancient mechanism to detoxify sulfide or to regulate RSS and along with catalase may continue to do so in contemporary organisms.	Hydrogen Sulfide	25-28	superoxide dismutase 1	Homo sapiens	43-46