PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34111175-9	2021	RRM1 inhibition with specific siRNA or hydroxyurea enhanced the cytotoxic effects of gemcitabine for pancreatic cancer cells.	Hydroxyurea	39-50	ribonucleotide reductase catalytic subunit M1	Homo sapiens	0-4	
15670581-7	2005	We found that the activities of hRRM2/hRRM1 and p53R2/hRRM1 were decreased by hydroxyurea in a dose-dependent manner.	Hydroxyurea	78-89	ribonucleotide reductase catalytic subunit M1	Homo sapiens	38-43	
15670581-7	2005	We found that the activities of hRRM2/hRRM1 and p53R2/hRRM1 were decreased by hydroxyurea in a dose-dependent manner.	Hydroxyurea	78-89	ribonucleotide reductase catalytic subunit M1	Homo sapiens	54-59	
15670581-9	2005	In the presence of Fe(III) and reductants, less inhibition of enzymatic activity by hydroxyurea was observed, especially for p53R2/hRRM1.	Hydroxyurea	84-95	ribonucleotide reductase catalytic subunit M1	Homo sapiens	131-136	
24434653-4	2014	In response to hydroxyurea, CHK1 was delocalized from the centrosome by RRM1 depletion.	Hydroxyurea	15-26	ribonucleotide reductase catalytic subunit M1	Homo sapiens	72-76