PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11462976-0 2001 Synthesis and SAR of a new series of COX-2-selective inhibitors: pyrazolo[1,5-a]pyrimidines. pyrazolo(1,5-a)pyrimidine 65-91 sarcosine dehydrogenase Homo sapiens 14-17 26349627-0 2015 Discovery and SAR of novel pyrazolo[1,5-a]pyrimidines as inhibitors of CDK9. pyrazolo(1,5-a)pyrimidine 27-53 sarcosine dehydrogenase Homo sapiens 14-17 24091081-1 2013 The synthesis and hit-to-lead SAR development from a pyrazolo[1,5-a]pyrimidine-derived hit 5 to the identification of a series of potent, pan-Pim inhibitors such as 11j are described. pyrazolo(1,5-a)pyrimidine 53-78 sarcosine dehydrogenase Homo sapiens 30-33 21094607-3 2011 Continued SAR development of the pyrazolo[1,5-a]pyrimidine core at the C5 and C6 positions, in conjunction with previously disclosed SAR at the C3 and C7 positions, led to the discovery of potent and selective CHK1 inhibitors. pyrazolo(1,5-a)pyrimidine 33-58 sarcosine dehydrogenase Homo sapiens 10-13 19200741-6 2009 We will present the synthesis, biological activities and SAR study of a series of pyrazolo[1,5-a]pyrimidines with an optimized phenyl amide moiety at the C-7 position. pyrazolo(1,5-a)pyrimidine 82-108 sarcosine dehydrogenase Homo sapiens 57-60