PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8079969-7	1994	Hemodialysis with cuprophane induced an increase in C5a concentration and in the expression of CD11b and MoF11 Ag, which were maximal after 15 minutes of hemodialysis, at the nadir of neutropenia.	cuprammonium cellulose	18-28	complement C5a receptor 1	Homo sapiens	52-55	
7890436-2	1994	The mean C5a level during Cuprophan dialysis was 29.9 +/- 0.63 ng/ml (Mean +/- SEM), while for the cellulose triacetate dialysis was 3.09 +/- 0.7 ng/ml.	cuprammonium cellulose	26-35	complement C5a receptor 1	Homo sapiens	9-12	
1379278-8	1992	Markedly elevated plasma levels of C5a des Arg were found in blood returning from the dialyzer following contact with cuprophane membranes.	cuprammonium cellulose	118-128	complement C5a receptor 1	Homo sapiens	35-38	
8088929-2	1993	The rise in plasma C3a and C5a was intense during haemodialysis with CU, but mild with PAN.	cuprammonium cellulose	69-71	complement C5a receptor 1	Homo sapiens	27-30	
1996568-4	1991	Our data suggest that hemodialysis with cuprophane membrane is associated with monocyte and PMNL activation as shown by production of ROS coincident with peak activation of the complement cascade; these granulocytes become refractory to further stimulation with C5a and FMLP during dialysis.	cuprammonium cellulose	40-50	complement C5a receptor 1	Homo sapiens	262-265	
18475443-1	1992	Cuprophane membranes during haemodialysis significantly increase the plasma levels of C5a(desArg) (maximal 55 mug C5a(adesArg)/1 blood after 30 min) whereas Hemophane or Polysulphonemembranes induce only low plasma levels of C5a(desArg).	cuprammonium cellulose	0-10	complement C5a receptor 1	Homo sapiens	86-97	
18475443-1	1992	Cuprophane membranes during haemodialysis significantly increase the plasma levels of C5a(desArg) (maximal 55 mug C5a(adesArg)/1 blood after 30 min) whereas Hemophane or Polysulphonemembranes induce only low plasma levels of C5a(desArg).	cuprammonium cellulose	0-10	complement C5a receptor 1	Homo sapiens	225-236	
1866069-2	1991	Cuprophane induced marked leukopenia with striking plasma generation of C5a.	cuprammonium cellulose	0-10	complement C5a receptor 1	Homo sapiens	72-75	
3699914-2	1986	CU membranes caused the most intense complement activation with C3a, C3d, and C5a levels peaking 15 min after beginning dialysis.	cuprammonium cellulose	0-2	complement C5a receptor 1	Homo sapiens	78-81	
2348571-4	1990	Plasma C5a levels were higher in CA and Cu than in EVA.	cuprammonium cellulose	40-42	complement C5a receptor 1	Homo sapiens	7-10	
3184764-2	1988	During hemodialysis on new cuprophan membranes raised levels not only of C3a, but in addition of activated C3, C5a, and Ba were demonstrated.	cuprammonium cellulose	27-36	complement C5a receptor 1	Homo sapiens	111-114	
3730166-2	1986	Cuprophan induced a marked leukopenia with significant plasma C5a generation.	cuprammonium cellulose	0-9	complement C5a receptor 1	Homo sapiens	62-65	
8671854-6	1996	Moreover, incubation of whole blood with recombinant C5a led to an increased monocyte CD14 expression supporting a role for complement activation in the rapid cuprophane-induced CD14 upregulation.	cuprammonium cellulose	159-169	complement C5a receptor 1	Homo sapiens	53-56	
6609269-1	1983	Measurable complement activation resulting in the formation of both C3a and C5a anaphylatoxins was observed in 12 patients undergoing maintenance dialysis treatment with cuprophan hollow fiber dialyzers.	cuprammonium cellulose	170-179	complement C5a receptor 1	Homo sapiens	76-79	
6609270-1	1983	Hemodialysis of 11 endstage renal failure patients with new cuprophan hollow fiber dialyzers produced significant leukopenia as well as increased plasma levels of both C3a and C5a antigens during the initial phases of the procedure.	cuprammonium cellulose	60-69	complement C5a receptor 1	Homo sapiens	176-179